Results 321 to 330 of about 592,784 (368)

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp, Elizabeth A. VanSickle, Julianne Michael, Chad R. Schultz, Kelly Nguyen, Melissa Hoefer, Surender Rajasekaran, André S. Bachmann   +7 more
wiley   +1 more source

Quantifying the impacts of volume-based procurement policy on spatial accessibility of antidepressants via generic substitution: A four-city cohort study using drug sales data. [PDF]

PLoS One
Xue A, Xue Q, Fu J, Fan K, Zhang J, Cai P, Kuang Y, Chen Y, Zhou J, Jiang B.   +9 more
europepmc   +1 more source

Varieties of digitalisation? A comparison of employment services digitalisation in the UK and Australia

Australian Journal of Social Issues, EarlyView.
Abstract This article examines the digitalisation of employment services in the UK and Australia, countries that have been on similar policy trajectories with respect to the development of quasi‐markets and increased digitalisation. The article deploys comparative mixed methods comprising surveys of employment service providers and interviews with ...
Jo Ingold, Chris Forde, David Robertshaw
wiley   +1 more source

Evaluating non-utilization of deceased donor kidneys in Korea. [PDF]

Sci Rep
Oh S, Kim K, Na O, Ha J, Koo TY, Yang J.
europepmc   +1 more source

Supporting the Recovery of NDIS Participants With Psychosocial Disability: A Narrative Literature Review

Australian Journal of Social Issues, EarlyView.
ABSTRACT This narrative literature review examines key issues surrounding psychosocial disability support in the National Disability Insurance Scheme (NDIS). It highlights the NDIS's neoliberal approach to support, which has underpinned a lack of clarity around the conceptualisation of psychosocial disability and recovery.
Johnny Choi, Kathy Ellem, John Drayton
wiley   +1 more source

Analysis of Unused Organ Donors in the Netherlands: Older Donor Age Associated With Higher Risk of Non-Utilization. [PDF]

Transpl Int
Chotkan KA, Kuiper MA, Alwayn IPJ, Heemskerk MBA, Braat AE, Jansen NE.   +5 more
europepmc   +1 more source

Effects of Nighttime Procurement and Transplantation on Outcomes Following Heart Transplantation. [PDF]

Clin Transplant
Hong Y, Hess NR, Dorken-Gallastegi A, Abdullah M, Iyanna N, Nasim U, Sultan I, Hickey GW, Keebler ME, Kaczorowski DJ.   +9 more
europepmc   +1 more source

Associations of Historic Residential Pesticide Proximity With Proinflammatory Cytokine Levels in a Patient Population With and Without Chronic Rhinosinusitis (CRS)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Residential proximity to commercial pesticide application has been associated with increased odds of developing chronic rhinosinusitis (CRS) with in vitro studies demonstrating cytotoxic dose‐dependent effects on sinonasal epithelia.
Melodyanne Y. Cheng, Kimberly C. Paul, Jakob L. Fischer, Myles G. Cockburn, Laura K. Thompson, Hong‐Ho Yang, Jeffrey D. Suh, Marilene B. Wang, Jivianne T. Lee   +8 more
wiley   +1 more source

A review of human factors and infusion pumps: lessons for procurement. [PDF]

Front Digit Health
Herrero L, Cano M, Ratwani R, Sánchez L, Sánchez B, Sancibrián R, Peralta G.   +6 more
europepmc   +1 more source

The impact of the centralized volume-based procurement policy on Chinese pharmaceutical manufacturing firms' R&D investment: A difference-in-differences approach. [PDF]

PLoS One
Qiu F, Chen S, Li Y, Wang X, Zhu M.
europepmc   +1 more source