Results 51 to 60 of about 289,430 (341)

Warehouse management practices and business performance of small-scale grapes processing firms: evidence from Tanzania

open access: yesCogent Business & Management
This paper examines the relationship between warehouse management practices including material handling, storage, inventory, and packaging and the business performance of small-scale grapes processing firms in Dodoma Region, Tanzania.
Debora Chelestino Kisinga   +2 more
doaj   +1 more source

Bureaucrats and Public Procurement [PDF]

open access: yesSSRN Electronic Journal, 2001
This paper deals with a Niskanen type of public-procurement agency. It is shown that the procurement game should be separated into an investment game and a project game, the first game to be played before nature determines the actual realizations of benefit and costs of the project, the second game to be played afterward.
openaire   +6 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Saudi Arabia’s Journey toward Net-Zero Emissions: Progress and Challenges

open access: yesEnergies, 2023
Combating climate change by reducing greenhouse gas (GHG) emissions has become an obligation for countries that ratified the Paris Agreement. Saudi Arabia, as a member of the Paris Agreement, pledged to achieve net zero emissions (NZE) by 2060.
Mazen A. Al-Sinan   +2 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

The Europeanisation of Good Neighborly Relations and Regional Cooperation Criteria: A Comparison between Albania and North Macedonia

open access: yesAnalele Universităţii din Oradea. Relaţii Internaţionale şi Studii Europene, 2023
Good neighbourly relations and regional cooperation demand that all the bilateral relations of a country be stable and that all the disputes are to be resolved before the signing of the Accession Treaty.
Geri PILACA
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Order management practices and small-scale grape processing firms’ performance: the moderating effect of logistics capabilities

open access: yesAfrican Business Management Journal
This study examines the moderating effect of logistics capabilities on the relationship between order management practices and the performance of small-scale grapes processing firms.
Debora Chelestino Kisinga   +2 more
doaj   +1 more source

Self-organisation, adaptability, organisational networks and inter-organisational coordination: empirical evidence from humanitarian organisations in Uganda [PDF]

open access: yesJournal of Humanitarian Logistics and Supply Chain Management, 2020
Purpose – To coordinate humanitarian organisations with different mandates that flock the scenes of disasters to save lives and respond to varied needs arising from the increased number of victims is not easy.
Henry Mutebi   +3 more
doaj   +1 more source

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