Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi +6 more
wiley +1 more source
Effects of Cocoa Antioxidants in Type 2 Diabetes Mellitus
Type 2 Diabetes mellitus (T2D) is the most common form of diabetes and one of the most common chronic diseases. Control of hyperglycaemia by hypoglycaemic drugs is insufficient in for patients and nutritional approaches are currently being explored ...
Sonia Ramos +2 more
doaj +1 more source
An analysis method for flavan-3-ols using high performance liquid chromatography coupled with a fluorescence detector [PDF]
Procyanidins belong to a family of flavan-3-ols, which consist of monomers, (+)-catechin and (-)-epicatechin, and their oligomers and polymers, and are distributed in many plant-derived foods.
Ashida, Hitoshi +3 more
core +2 more sources
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi +5 more
wiley +1 more source
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Paul Besrukow +3 more
wiley +1 more source
Redox imbalance elevates the reactive oxygen species (ROS) level in cells and promotes age-related diseases. Superoxide dismutases (SODs) are antioxidative enzymes that catalyze the degradation of ROS. There are three SOD isoforms: SOD1/CuZn-SOD, SOD2/Mn-
Takahiko Shimizu +5 more
doaj +1 more source
Dimeric procyanidins as modulators of airway inflammation in the context of allergic asthma : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Human Physiology at Massey University, Manawatū, Palmerston North, New Zealand [PDF]
Procyanidins are polyphenolic compounds that have come to be known as biologically active in the context of promoting human health. Epidemiological evidence suggests that populations that consume diets rich in procyanidins are less susceptible to ...
Coleman, Sara L
core
Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort [PDF]
Cocoa flavanols (CF) positively influence physiological processes in ways that suggest their consumption may improve aspects of cognitive function. This study investigated the acute cognitive and subjective effects of CF consumption during sustained ...
Andrew B Scholey +20 more
core +1 more source
Abstract BACKGROUND Chinese steamed bread (CSB) is a traditional East Asian staple. Its texture and nutrition depend on the gluten and starch content of the wheat flour that it contains. Incorporation of golden kiwifruit, which is rich in dietary fiber, vitamin C, and phenolic antioxidants, offers a novel fortification strategy.
Jiecheng Li +2 more
wiley +1 more source
Characterisation of polyphenols by HPLC-PAD-ESI/MS and antioxidant activity in Equisetum telmateia [PDF]
The antioxidant activity of an aqueous extract (infusion) and respective ethyl acetate fraction of Equisetum telmateia Ehrh. (Equisetaceae), a plant used in traditional medicine for its anti-inflammatory and diuretic properties, has been evaluated by ...
Amaral, Maria Teresa +4 more
core +1 more source

