Results 91 to 100 of about 47,670 (237)

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Estimating Cognitive Impairment in Bipolar Disorder: Should We Account for Premorbid IQ?

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Cognitive impairment estimations traditionally rely on the deviation of current cognitive performance from population norms (normative approach). Since bipolar disorder (BD) has been associated with above‐average premorbid cognitive functioning in some studies, this approach might underestimate the extent of cognitive impairment ...
Dimosthenis Tsapekos   +5 more
wiley   +1 more source

Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI. This study aims to examine potential interactions between sex and diagnosis across a broad range of variables, to compare ...
Maria Serra‐Navarro   +35 more
wiley   +1 more source

Pineal Gland Volume, Sleep Quality, and Psychiatric Disorders: A Systematic Review and Meta‐Analysis

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Disturbances in sleep and circadian rhythms are features of several psychiatric disorders. The pineal gland regulates these rhythms via melatonin, with pineal gland volume (PGV) serving as a structural proxy. We conducted a meta‐analysis to synthesize evidence on differences in PGV between patients with psychiatric disorders and ...
Sophie Bolwig, Kristian H. R. Jensen
wiley   +1 more source

A call for action: Closing the evidence gap in management of stimulant‐induced psychosis

open access: yesAddiction, EarlyView.
Abstract Background Stimulant‐induced psychosis (StIP) is emerging as one of most pressing health challenges. Over the past two decades, stimulant‐related harms and psychiatric care demands have risen sharply. Individuals with StIP often present with severe agitation and high suicide risk, and up to half progress to chronic psychotic illness within two
Anne Bouthillier   +3 more
wiley   +1 more source

Individualized brain radiomics-based network tracks distinct subtypes and abnormal patterns in prodromal Parkinson's disease

open access: yesNeuroImage
Individuals in the prodromal phase of Parkinson's disease (PD) exhibit significant heterogeneity and can be divided into distinct subtypes based on clinical symptoms, pathological mechanisms, and brain network patterns.
Lin Hua   +4 more
doaj   +1 more source

Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore   +2 more
wiley   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber   +4 more
wiley   +1 more source

Prodromal Symptoms in Acute Myocardial Infarction in City of Birjand

open access: yesمجله اپیدمیولوژی ایران, 2008
Background and objective: Acute myocardial infarction (AMI) is the most prevalent cause of mortality in the world today. Sometimes before an acute phase of AMI there are certain prodromal symptoms.
HR Mashreghimoghadam   +2 more
doaj  

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