Results 131 to 140 of about 47,670 (237)

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu   +4 more
wiley   +1 more source

Incidence and clinical manifestations of sudden death in young adults: a two-decade, nationwide, retrospective, cross-sectional study. [PDF]

open access: yesResusc Plus
Maayan Y   +12 more
europepmc   +1 more source

Low Sensitivity of Neuropsychological Scales Hinder Detection of Potential Benefit of Treatments in Alzheimer's Disease: A Position Paper. [PDF]

open access: yesEur J Neurol
ABSTRACT Background Despite the advent of Disease Modifying Therapies (DMTs) for Alzheimer's Disease (AD), the approval and commercialization of anti‐amyloid monoclonal antibodies has been slow and contentious, particularly in Europe. The primary source of debate is the discrepancy between robust biological effects—namely, effective β‐amyloid clearance—
Luzzi S, Snowden JS.
europepmc   +2 more sources

rTCT: Rodent Triangle Completion Task to Facilitate Reverse Translational Study of Path Integration

open access: yesHippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT Path integration is navigation in the absence of environmental landmarks and is a primary cognitive mechanism underlying spatial memory. Path integration performance is primarily assessed in humans using the Triangle Completion Task (TCT). In humans, TCT has shown promise for the early diagnosis of Alzheimer's disease.
Stephen Duncan   +13 more
wiley   +1 more source

Fingerprints Encode Risk for Bipolarity

open access: yesBipolar Disorders, Volume 28, Issue 3, May 2026.
ABSTRACT Background Fingerprint patterns are developed during pregnancy and share a common embryogenic origin with the central nervous system. Considering the observed relationship between prenatal abnormalities and higher risk for schizophrenia, we previously built fingerprint‐based algorithms achieving validation accuracies up to 70% in a large ...
Raymond Salvador   +25 more
wiley   +1 more source

Sleep in Early Psychosis and Bipolar Disorder: Preliminary Results on Actigraphic and Self-Reported Markers of Vulnerability. [PDF]

open access: yesEarly Interv Psychiatry
Baldini V   +9 more
europepmc   +1 more source

Computed tomography identifies the proximodorsomedial subchondral bone of equine central tarsal bones as a predilection site for sclerosis, demineralisation and associated fractures

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 797-804, May 2026.
Abstract Background The distribution pattern of central tarsal bone (CTB) changes has not been described, except for slab‐ and dorsomedial–plantarolateral fractures. Objectives To describe CTB changes in CT and document their distribution and associations. Study Design Retrospective case series.
Sandra Campana   +3 more
wiley   +1 more source

Glial cytokine modulation improves sleep and circadian disruption in female SAA knock‐in mice of Alzheimer's‐related pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Sleep and circadian disturbances are early Alzheimer's disease (AD) features, yet mechanisms linking amyloid pathology, neuroinflammation, and sex differences remain unclear. METHODS We longitudinally assessed sleep, circadian rhythms, and cognition in female and male hAPPSAA knock‐in and control mice from 2 to 19 months using ...
Teresa Macheda   +18 more
wiley   +1 more source

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