Results 151 to 160 of about 47,670 (237)

Premature Neuroimmune and Redox-Inflammatory Breakdown at the Prodromal Stage in Male and Female Triple-Transgenic Alzheimer's Disease Mice. [PDF]

Diseases
Giménez-Llort L, Vida C, Félix J, Quer-Palomas S, Manassra R, De la Fuente M.   +5 more
europepmc   +1 more source

Catheter Ablation for Frequent Premature Ventricular Contractions or Paroxysmal Supraventricular Tachycardia With Vagal Bradycardia: A New Clinical Application of Superior Vena Cava–Aorta Ganglionated Plexus Modification

Clinical Cardiology, Volume 49, Issue 4, April 2026.
This study demonstrates that combined RFCA and right atrial Ao‐SVC GP ablation provides a one‐stop, innovative solution for patients with vagal bradycardia and concomitant tachyarrhythmias, significantly improving symptoms and reducing syncope. ABSTRACT Background Frequent premature ventricular contractions (PVCs) or paroxysmal supraventricular ...
Xinai Meng, Senlin Huang, Liwei He, Tian Liu, Yanjia Chen, Huahua Li, Xingfu Huang   +6 more
wiley   +1 more source

Cognitive Impairment, Dementia and Depression in Older Adults. [PDF]

J Clin Med
Jang YJ, Chang JH, Moon DU, Jeon HJ.
europepmc   +1 more source

Predicting Long‐Term Depression Progression in Parkinson's Disease: A Machine‐Learning Survival Analysis and Risk Score

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
We developed and internally validated a machine learning–based survival model for predicting long‐term progression of dPD. Supported by SHAP analysis, the model identified that depressive symptom severity, cognitive impairment, and autonomic dysfunction were the main key clinical predictors for dPD progression.
Defu Liu, Chong Qi, Jiansong Huang, Hutao Xie, Yutong Zhuang, Quan Zhang, Xuemin Zhao, Tianqi Hu, Guofan Qin, Yue Lu, Xin Zhang, Sizhe Li, Mingyu Yang, Jianguo Zhang, Yin Jiang   +14 more
wiley   +1 more source

Correction to: Longitudinal neuromelanin changes in prodromal and early Parkinson's disease in humans and rat model. [PDF]

Brain Commun
europepmc   +1 more source

Depression as a Prodromal Symptom of Pancreatic Cancer: A Narrative Review. [PDF]

Cancers (Basel)
Deori C, Andreis F, Giubileo V, Noventa S, Oneda E, Meriggi F, Zaniboni A.   +6 more
europepmc   +1 more source

The Brain‐Gut Axis in Parkinson's Disease Pathology

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Exposure to environmental toxins induces gut dysbiosis, increases intestinal epithelial barrier permeability, immune activation, and oxidative stress, promoting α‐syn misfolding and propagation. Brainstem DMV neurons exhibit α‐syn pathology, dysregulating neuronal excitability and vagal control of GI functions.
Kudret Selin Ozkaya, Kirsteen N. Browning   +1 more
wiley   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Anticipating Clinical Onset in Multiple Sclerosis: Challenges and Opportunities. [PDF]

J Pers Med
Nociti V, Romozzi M.
europepmc   +1 more source

Dynamic Alterations of Functional Systems in Alzheimer's Disease: A Co‐Activation Pattern Analysis

Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.
State 3 exhibited significantly reduced persistence and resilience in both MCI and AD compared to CU. Individuals with MCI and AD showed reduced transition probability from State 2 to State 5 and decreased self‐transitions in State 3. Graph theoretical results corresponded well to the findings of the above CAP analysis.
Pan Wang, Mengfan Xue, Yingyin Mao, Chunyan Wang, Xing Yao, Bharat B. Biswal   +5 more
wiley   +1 more source