Results 171 to 180 of about 47,670 (237)

Astrocyte Proximity Protects Synapses From Human Amyloid‐Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease

European Journal of Neuroscience, Volume 63, Issue 7, April 2026.
Alzheimer's disease (AD) is the most common cause of dementia, affecting over 35 million people worldwide. A key feature of AD is the loss of synapses—the connections between brain cells—which strongly correlates with cognitive decline. We sought to investigate the role of astrocytes in mouse organotypic cultures challenged with brain homogenate (BH ...
Francesco Gobbo, Declan King, Jane Tulloch, Davide Gobbo, Calum Bonthron, Soraya Meftah, Caleb Stoddart‐Campbelton, Arisa Tamura, Jamie Rose, Colin Smith, Claire Durrant, Tara L. Spires‐Jones   +11 more
wiley   +1 more source

Rethinking Femoral Head Biopsies in Geriatric Hip Fractures: Financial Burden vs Clinical Outcomes. [PDF]

Geriatr Orthop Surg Rehabil
Yung CSY, Fang C, Cheng HM, Leung F, Lau TW.   +4 more
europepmc   +1 more source

Interictal and Ictal Cognitive Performance in Episodic and Chronic Migraine

European Journal of Neurology, Volume 33, Issue 4, April 2026.
Migraine is not only a pain disorder but a dynamic network disorder with measurable cognitive consequences. Interictally, working memory impairment was observed in episodic migraine, while chronic migraine showed broader deficits in attention and executive functions.
Esra Kochan Kizilkilic, Bekir Burak Kılboz, Serap Üçler Yaman   +2 more
wiley   +1 more source

The Use of a Digital Social Forum in a Parkinson's Disease Risk Cohort: A Thematic Analysis of Forum Messages. [PDF]

Parkinsons Dis
Smith LJ, Jeyaganesh J, Li X, Gill A, Schrag A, Huxford B, Simonet C, Pérez-Carbonell L, Noyce AJ, Simoni A.   +9 more
europepmc   +1 more source

Postprandial Hypotension—Methods for the Evaluation and Management

Geriatrics &Gerontology International, Volume 26, Issue 4, April 2026.
Postprandial hypotension (PPH) is highly prevalent in older patients; however, its diagnosis remains challenging due to the absence of a consensus guideline for diagnostic criteria. Lifestyle modification is the first‐line management, taking into account the pathophysiology underlying PPH and the coexisting conditions of orthostatic hypotension and ...
Joji Ishikawa, Ayumi Toba, Shutaro Futami, Kazumasa Harada   +3 more
wiley   +1 more source

Integrating gepants into clinical practice for the acute treatment of migraine

Headache: The Journal of Head and Face Pain, Volume 66, Issue 4, Page 976-989, April 2026.
Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton, David W. Dodick, Linda Davis, Stephanie J. Nahas, Peter J. Goadsby   +4 more
wiley   +1 more source

Metabolic brain networks in dementia with Lewy bodies: from prodromal to manifest disease stages. [PDF]

J Neurol Neurosurg Psychiatry
Perovnik M, Simončič U, Jamšek J, Gregorič Kramberger M, Brumberg J, Meyer PT, Perani D, Caminiti SP, Brendel M, Stockbauer AC, Camacho V, Alcolea D, Vandenberghe R, Van Laere K, Ko JH, Lee CS, Pardini M, Lombardo L, Padovani A, Pilotto A, Ochoa-Figueroa MA, Davidsson A, Cháfer-Pericás C, Álvarez-Sánchez L, Garibotto V, Lemstra AW, Ferreira D, Morbelli SD, Tang CC, Eidelberg D, Trošt M, Alzheimer’s Disease Neuroimaging Initiative.   +31 more
europepmc   +1 more source

Advances in hiPSC‐Derived Brain Organoids as a Model to Study Neuroinflammation in Alzheimer's Disease

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Brain organoids and assembloids derived from human induced pluripotent stem cells (hiPSCs) represent a striking advance in biomedical research. These technologies allow a more accurate mimicry of the three‐dimensional cellular environment in vitro, enabling detailed investigations of Alzheimer's disease (AD) pathological features, such as β‐amyloid ...
Esther Marques Alves Maciel, Nathália Costa Silva, Luiz Gustavo Pontes Santos, Fabiola M. Ribeiro   +3 more
wiley   +1 more source

The Relationship Between Sleep Quality and Prodromal Symptoms in Euthymic Patients with Bipolar Disorder. [PDF]

Noro Psikiyatr Ars
Fidan YS, İzci F, Aslan M, Çallı SY, Şakiroglu MA, Pire B, Kızılsert A.   +6 more
europepmc   +1 more source