Results 61 to 70 of about 47,670 (237)

Menetrier's: A pediatric chronic state of disease with a possible heritable form

JPGN Reports, EarlyView.
Abstract Menetrier's disease (MD) is a rare, typically transient, hypertrophic gastropathy with under 1000 adult cases and 50 pediatric cases known worldwide. Pediatric cases most often present with an infectious etiology. We present a case of a teenage male expressing a chronic state of disease without infectious origin.
MariaElena Terzis, Anna Furr, Julia Fritz   +2 more
wiley   +1 more source

Prodromal States in Schizophrenia

Comprehensive Psychiatry, 2000
The vulnerability-stress-coping (VSC) model is the most influential heuristic concept in understanding the course of schizophrenia, whose prodromal status still offers unsolved conceptual and methodological issues. Improved knowledge about the prodromal phase would provide a better understanding of the developing psychopathology and psychophysiology of
W, Gaebel, M, Jänner, N, Frommann, A, Pietzcker, W, Köpcke, M, Linden, P, Müller, F, Müller-Spahn, J, Tegeler   +8 more
openaire   +2 more sources

Evaluating the Role of α‐Synuclein Seed Amplification as a Disease Progression Marker: Evidence and Uncertainties

Movement Disorders Clinical Practice, EarlyView.
Abstract Background α‐synuclein seeding amplification assay (α‐synuclein SAA) development as a diagnostic biomarker for Parkinson's disease (PD) has shown promising results over the past decade. However, the utility of these assays in the prediction of disease progression is unclear.
Daniel Belete, Christian Mattjie, Brook Huxford, Jonathan P. Bestwick, Alastair J. Noyce, Cristina Simonet   +5 more
wiley   +1 more source

Faster decline of very prodromal dementia with Lewy bodies when amyloid positive

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION The cognitive and neuroimaging evolution during dementia with Lewy bodies (DLB) from the prodromal phase (Pro‐DLB; subjective cognitive impairment [SCI] to mild cognitive impairment [MCI]) according to amyloid beta (Aβ) status is poorly ...
Frédéric Blanc, Vincent Bouteloup, Claire Paquet, Marie Chupin, Florence Pasquier, Audrey Gabelle, Mathieu Ceccaldi, Paulo Loureiro deSousa, Pierre Krolak‐Salmon, Renaud David, Clara Fischer, Jean‐François Dartigues, David Wallon, Olivier Moreaud, Mathilde Sauvée, Catherine Belin, Claire Roubaud Baudron, Anne Botzung, Alix Ravier, Catherine Demuynck, Izzie Namer, Marie‐Odile Habert, Olivier Bousiges, Benoît Schorr, Candice Muller, Nathalie Philippi, Geneviève Chêne, Benjamin Cretin, Jean‐François Mangin, Carole Dufouil   +29 more
doaj   +1 more source

Reward processing deficits arise early in familial frontotemporal dementia

Frontiers in Neuroscience
Reward processing involves evaluation of stimuli to inform what an individual works to pursue or avoid. Patients with behavioral variant frontotemporal dementia (bvFTD) often display reward processing changes, including insensitivity to aversive stimuli.
Noah G. Cryns, Emily G. Hardy, Ashlin R. K. Roy, Samir Datta, Andrzej Sokolowski, Virginia E. Sturm, Joel H. Kramer, Adam L. Boxer, Bruce L. Miller, Howard J. Rosen, David C. Perry   +10 more
doaj   +1 more source

Relation between duration of the prodromal phase and renal damage in ANCA-associated vasculitis

BMC Nephrology, 2017
Background In ANCA-associated vasculitis the acute phase of the disease is often preceded by prodromal symptoms. The aim of the present study was to analyze the relation between the duration of the prodromal phase and renal damage.
Eline Houben, Stefanie L. Groenland, Joost W. van der Heijden, Alexandre E. Voskuyl, Hiëronymus J. Doodeman, Erik L. Penne   +5 more
doaj   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

Early Parkinson’s Disease Prediction Using rS-fMRI Functional Connectivity and Autoencoder Graph Convolutional Network

IEEE Access
Early identification of prodromal Parkinson’s disease (PD) is critical, as interventions at this stage can significantly alter its course. We propose a deep learning framework that combines resting-state functional MRI (rs-fMRI) data and a Graph ...
Lesbia Lopez Limas, Vidya Manian
doaj   +1 more source

The Inaugural NIH‐Wide Strategic Plan for Autoimmune Disease Research (Fiscal Years 2026–2030)

Arthritis &Rheumatology, EarlyView.
Victoria K. Shanmugam, Carmen Ufret‐Vincenty, Xinrui Li, Janine A. Clayton   +3 more
wiley   +1 more source

Genetic and Pathological Testing Attitudes for Parkinson's Disease in At‐Risk Relatives

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is increasingly recognized as a neurodegenerative disorder with a broad clinical spectrum and diverse biomarkers enabling early detection. α‐synuclein seed amplification assays (SAA) and genetic testing now allow identification of PD pathology in asymptomatic individuals.
Tal Weil, Anat Mirelman, Roy N. Alcalay, Nurit Omer, Penina Ponger, Avner Thaler   +5 more
wiley   +1 more source