Effects of High Intensity Ultrasound Stimulation on the Germination Performance of Caper Seeds [PDF]
The caper bush has developed different mechanisms to survive in Mediterranean conditions, such as drought tolerance and seed dormancy. Many studies have been carried out to improve the germination of caper seeds, but ultrasound is one of the least ...
María Laura Foschi +3 more
doaj +2 more sources
Lactiplantibacillus plantarum: a new example of inclusion body producing bacteria [PDF]
Background Lactic Acid Bacteria such as Lactococcus lactis, Latilactobacillus sakei (basonym: Lactobacillus sakei) and Lactiplantibacillus plantarum (basonym: Lactobacillus plantarum) have gained importance as recombinant cell factories.
Ricardo Baltà-Foix +6 more
doaj +2 more sources
Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2 [PDF]
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Martín‐Sánchez A +6 more
europepmc +2 more sources
AAV-mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice. [PDF]
Intraventricular administration of AAV vectors expressing secreted and transmembrane Klotho isoforms, rescued accelerated aging phenotype of SAMP8 mice. An improvement in cognitive and physical performance, recovery of epigenetic, inflammatory and senescence markers, as well as structural changes in long bones of these mice was detected.
Roig-Soriano J +6 more
europepmc +2 more sources
Advances in gene therapy for Lafora disease: Intravenous recombinant adeno-associated virus-mediated delivery of EPM2A and EPM2B genes. [PDF]
Intravenous gene therapy with rAAV2/9P31 vectors delivering EPM2A or EPM2B reversed Lafora disease pathology and restored neuronal function in two mouse models. The approach showed comparable or superior efficacy to intracerebroventricular delivery, with no long‐term toxicity, supporting its translational potential.
Zafra-Puerta L +8 more
europepmc +2 more sources
Downstream process design for Gag HIV‐1 based virus‐like particles
Abstract Virus‐like particles‐based vaccines have been gaining interest in recent years. The manufacturing of these particles includes their production by cell culture followed by their purification to meet the requirements of its final use. The presence of host cell extracellular vesicles represents a challenge for better virus‐like particles ...
Elianet Lorenzo +3 more
wiley +1 more source
La producció cerealícola a les petites explotacions pageses des Pla de Mallorca (1850-1851)
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Enric Tello
doaj +1 more source
‘A just price is future’: The capital–life conflict in a viticulture region (El Penedès)
Abstract El Penedès is an area of Catalonia (northeastern Spain) characterised by its viticulture activity. Its landscape and territorial identity are marked by vineyards and the creation of still and sparkling wines such as cava. This article analyses the tensions between the three dimensions of sustainability (economic, sociocultural and ...
Patricia Homs Ramírez de la Piscina
wiley +1 more source
Abstract Hypsodont teeth molars develop in a short lapse of time. Both dentine and enamel dental tissues do not regenerate once formed. This fact allows the reconstruction of isotopic sequences covering short moments of the individual's life span, a useful approach in current zooarchaeological and paleontological studies.
Celia Díez‐Canseco +2 more
wiley +1 more source
Abstract The everyday difficulties faced by working‐class women, including access to food, are aggravated in critical periods, such as wars and economic crises. However, the Spanish Civil War (1936–1939) was accompanied by a revolution, in the Republican zones, where women opened spaces for their emancipation. By examining social reproduction practices
Marta Camps‐Calvet +2 more
wiley +1 more source

