Results 111 to 120 of about 4,501,132 (358)

Processing peracetic acid treated bloodmeal into bioplastic [PDF]

open access: yes, 2012
Renewable and biodegradable bioplastics can be produced from biopolymers such as proteins. Animal blood is a by-product from meat processing and is rich in protein. It is dried into low value bloodmeal and is used as animal feed or fertiliser.
Lay, Mark C.   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Research on performance evaluation method of oilfield multi-layer filter

open access: yesGongye shui chuli
To address the prevalent challenges of substandard treatment and modification difficulties in oilfield produced water multi-media filtration systems, by constructing a multiphase flow-coupled filtration dynamics model, this study systematically ...
WANG Yuxiao   +6 more
doaj   +1 more source

Investigating Fatigue Performance on the Foamed Asphalt Specimens Generated Using Different Foam Properties [PDF]

open access: yes, 2012
An evaluation of fatigue resistance for foamed asphalt mixture is very demanding since the binder is not continuously distributed on the aggregate surface and this mixtures contains water, the content of which dramatically affects the mechanical ...
Sunarjono, S. (Sri)
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Polarization induced water molecule dissociation below the first-order electronic-phase transition temperature

open access: yes, 2011
Hydrogen produced from the photocatalytic splitting of water is one of the reliable alternatives to replace the polluting fossil and the radioactive nuclear fuels.
Arulsamy, Andrew Das   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Who regulates it? Water policy and hydraulic fracturing in Texas

open access: yesTexas Water Journal, 2015
Hydraulic fracturing, the injection of a pressurized fluid mixture of mostly water, sand and a small amount of chemicals (frac fluids), increases extraction rates and recovery of oil or gas.
Margaret Cook   +2 more
doaj  

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