Results 101 to 110 of about 23,696 (283)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

An Incentive System for Salmonella Control in the Pork Supply Chain [PDF]

This paper presents a dynamic principal-agent analysis of an incentive system for Salmonella control in the pork supply chain. The incentive system determines quality premiums to the producer, testing frequencies for hogs delivered, as well as charges to
Backus, Ge B.C., King, Robert P.
core   +1 more source

Food Quality in Producer-Grazer Models: A Generalized Analysis

, 2010
Stoichiometric constraints play a role in the dynamics of natural populations, but are not explicitly considered in most mathematical models. Recent theoretical works suggest that these constraints can have a significant impact and should not be ...
Feudel, Ulrike, Gross, Thilo, Kooi, Bob W., Stiefs, Dirk, van Voorn, George A. K.   +4 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Characterising maize and intercropped maize spectral signatures for cropping pattern classification

International Journal of Applied Earth Observations and Geoinformation
Intercropping – the planting of more than one crop in the same plot of land – is a prevalent agricultural management practice which can be used for risk reduction.
Mbali Mahlayeye, Roshanak Darvishzadeh, Andrew Nelson   +2 more
doaj   +1 more source

ADOPTION OF BEST MANAGEMENT PRACTICES IN STOCKER CATTLE PRODUCTION [PDF]

This study identifies current production and management practices of Oklahoma stocker cattle producers and analyzes factors affecting the adoption of best management practices (BMPs) using chi-square analysis.
Doye, Damona G., Johnson, Rachel J., Lalman, David L., Peel, Derrell S., Raper, Kellie Curry   +4 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Effects of Insurance on Farmer Crop Abandonment [PDF]

Empirical evidence for the existence of moral hazard in the U.S. crop insurance program has been inconclusive. Here, we seek empirical evidence of moral hazard in the U.S. crop insurance program, departing from the established empirical literature in two
Chen, Shu-Ling, Miranda, Mario J.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Acceptance sampling plans based on percentiles for extended generalized exponential distribution with real data application

Journal of Radiation Research and Applied Sciences
In this paper, when the life test is truncated at a pre-determined time, new acceptance sampling plans (ASP) are developed based on percentile lifetime as a quality parameter for the extended generalized exponential distribution (EGED).
Amer Ibrahim Al-Omari, Ghadah A. Alomani
doaj   +1 more source