Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Speculative Trading in Energy Markets: Evidence from Macroeconomic Surprises. [PDF]
Boucher SP, Gagnon MH, Power GJ.
europepmc +1 more source
Comparing new final-demand producer price indexes with other government price indexes [PDF]
openaire +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Empirical applications of economic principles in producer price index analysis
The research analyses economic linkages of producer price indices of the construction industry in Australia and relationships between construction and house prices.
Cuijia. Fu (13786087)
core
Economic Entropy and Sectoral Dynamics: A Thermodynamic Approach to Market Analysis. [PDF]
Rojas Castillo WA +3 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Dynamic forecasting of China's carbon market prices by the coupling of macroeconomic indicators and LSTM model. [PDF]
Wang Y, Huo H, Liu X, Song F, Huang S.
europepmc +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Macroeconomic-aware forecasting of construction costs in developing countries: Using gated recurrent unit and long short-term memory deep learning framework. [PDF]
Alzara M +6 more
europepmc +1 more source

