Results 101 to 110 of about 143,442 (313)
EVALUATING PRIVATELY FUNDED PUBLIC RESEARCH: AN EXAMPLE WITH POULTRY AND EGGS [PDF]
A procedure is described for evaluating poultry and egg research projects. A peer review questionnaire and benefit-cost analysis are utilized incorporating elasticities from an econometric model for poultry and eggs.
Martinez, Stephen W., Norton, George W.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
NEW VARIETIES AND THE RETURNS TO COMMODITY PROMOTION: WASHINGTON FUJI APPLES [PDF]
The Fugi apple variety is relatively new in the U.S. As a new product, questions concern the relative impact of consumer learning by experience, by variety-specific promotion, or by generic apple promotion.
Patterson, Paul M., Richards, Timothy J.
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Optimal Copyright Protection: Civil Law vs. Criminal Law [PDF]
We consider optimal copyright protection strategies from the government and producer perspectives. Our model assumes that the government sets the penalty for infringement, and that the producer is responsible for monitoring illegal activity. We find that
Arai, Yasuhiro
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
RESEARCH AND ADVERTISING DECISIONS IN AN OPEN ECONOMY: THE CASE OF COLOMBIAN MILDS COFFEE [PDF]
Research and advertising investment both offer the potential to increase producer surplus. A model is developed that includes applied research and generic advertising with the aim of measuring marginal and optimal returns from each.
Goddard, Ellen W., Sellen, Daniel
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Partial privatization and environmental policies [PDF]
The paper compares emission tax and emission quota in a mixed duopoly when the partial privatization of a public firm is allowed. Furthermore, we consider the following two cases with regard to the objective of the public firm: (1) the public firm ...
Kato, Kazuhiko
core +1 more source
Debunking Mankiw, Episode I. Adam Smith, Paradoxical or Untrue? [PDF]
, 2016 En el seu Principles of Economics, Greg Mankiw, fent referència a Adam Smith, afirma que les forces de l’oferta i la demanda distribueixen els recursos de manera eficient: malgrat que cada persona compradora i cada venedora es preocupa únicament del ...
Bofill Soliguer, Pablo
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