Results 251 to 260 of about 1,544,891 (313)

Real-World Evidence From a Digital Health Treatment Program for Female Urinary Incontinence: Observational Study of Outcomes Following User-Centered Product Design. [PDF]

JMIR Form Res
Hall E, Keyser L, McKinney J, Pulliam S, Weinstein M.   +4 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

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Designer-moderated product design

IEEE Transactions on Engineering Management, 2001
A well-designed product can provide a firm with a competitive advantage that will enable it to achieve a higher market share and increased profits. Conjoint analysis procedures are often used for product design. Numerous methods have been developed to take conjoint data and produce optimal or near-optimal product designs.
Peter Tarasewich, Suresh K. Nair
openaire   +1 more source

Intelligent Product Design

Proceedings of the Tenth Annual ACM/IEEE International Conference on Human-Robot Interaction Extended Abstracts, 2015
Robot's appearance types could be classified into human-oriented robot and product-oriented robot. Human-oriented robot resembles human's appearance and behavior whereas product-oriented robot is an intelligent product that is laden with robotic technologies based on the existing product [1].
Han Nwi Lee, Yeseul Namkoung, Heather Jin Hee Kim, Seul Lee, Daun Jeong, Hyunji Seo, Soyeon Park, Kyeongah Lee, Sunbin Yang, Jimin Choi, Yeeun Kim, Jung-Ju Choi, Sonya S. Kwak   +12 more
openaire   +1 more source

Design for Product Adaptability

Concurrent Engineering, 2007
Adaptable design is a new design paradigm to create designs and products that can be easily changed to satisfy different requirements. Adaptable design aims at identifying the designs and products considering functionality, manufacturing efforts, customization, and environment friendliness.
Yi Li, Deyi Xue, Peihua Gu
openaire   +1 more source

Design formulae of product design production manufacturability

Science intensive technologies in mechanical engineering, 2020
There are shown basic drawbacks of the well-known factors of manufacturability. The formulae of manufacturability factors excluding mentioned drawbacks and taking into account the impact of product design characteristics upon complete laboriousness of its manufacturing are offered.
openaire   +1 more source