Results 141 to 150 of about 427,530 (307)

The importance of product innovation in maintaining a competitive advantage

open access: yesMednarodno Inovativno Poslovanje
Product innovation is crucial in creating and sustaining a competitive advantage for companies. Companies can differentiate themselves from competitors by constantly improving, introducing new products, and appealing to customers.
Ahmed Saeed Sarkar   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Impacts of Incoming Knowledge on Product Innovation: Technology Transfer in Auto-related Industries in Developing Economies [PDF]

open access: yes
This paper studies two questions on the role of networked sources of knowledge influential to product innovation. First: What is the extent of technology transferred through vertical linkages and public-private alliances, including university-industry ...
Tomohiro MACHIKITA, Yasushi UEKI
core  

The identification of dynamic product innovation opportunities using the multi-phase QFD: the customer requirement and technology development perspectives

open access: yesHumanities & Social Sciences Communications
Identifying product innovation opportunities is critical for companies to implement product innovation activities. However, existing studies primarily identify product innovation opportunities from the perspective of customer requirements or technology ...
Lu Zheng, Lin Sun, Zhen He, Shuguang He
doaj   +1 more source

A Quantitative Framework to Identify and Prioritize Opportunities in Biomedical Product Innovation: A Proof-of-Concept Study.

open access: yesJAMA Health Forum, 2023
Gressler LE   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Managing creative eco-innovation: Structuring outputs from eco-innovation projects

open access: yes, 2001
Increasing legislative pressures and consumer awareness of environmentally efficient products are causing businesses to look at Sustainable Product Design (SPD) as an opportunity to improve their products and processes.
McLaren, J, Jones, E, Harrison, DJ
core  

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