Results 231 to 240 of about 1,737,461 (304)

Enabling digital multifactorial risk assessment in primary care: an umbrella review and recommendations for design and implementation. [PDF]

BMJ Health Care Inform
Taylor LC, Peek N, Ercole A, Lyratzopoulos G, Usher-Smith JA.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Risk factors for intertrochanteric femoral fractures with concomitant lateral wall involvement in elderly women. [PDF]

Front Surg
Shi G, Hu Z, Xie Z, Gu J, Lu Q, Ling Z.
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

'Dad, I'm not even doing anything!': a qualitative inquiry into father‒child play dynamics. [PDF]

BMC Psychol
Alabay E, Kantekin Atabay Y.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Detailed composition of wax esters in mouse sebum and the involvement of FAR2 and AWAT2. [PDF]

iScience
Kuribayashi K, Jojima K, Yamamoto M, Takeda M, Kihara A.   +4 more
europepmc   +1 more source

Case Report: Glofitamab in the treatment of a patient with central nervous system-involved Burkitt lymphoma. [PDF]

Front Oncol
Huang Y, Jiang J, Lu J, Sun C, Qian J, You X, Lin Z.   +6 more
europepmc   +1 more source

Narrative strategies in live-streaming commerce: host storytelling, immersion, and impulse buying. [PDF]

Front Psychol
Wang M, Zhang W, Li Y.
europepmc   +1 more source