Results 141 to 150 of about 524,692 (354)

Conversational Topic Shifts and Topic Maintenance in Autistic and Neurotypical Children

open access: yesAutism Research, EarlyView.
ABSTRACT Topic maintenance and topic shifts are crucial components of conversation; however, existing research lacks a clear quantitative operationalization of these topic management skills. Previous studies suggest that autistic children are less likely than their neurotypical peers to maintain and elaborate on the interlocutor's prior topic, and that
Zuriñe Ábalos   +3 more
wiley   +1 more source

TAXATION, FINES, AND PRODUCER LIABILITY RULES: EFFICIENCY AND MARKET STRUCTURE IMPLICATIONS [PDF]

open access: yes
This paper addresses the comparative efficiency of liability rules and regulatory policy in competitive equilibria with endogenous product safety. Pigouvian taxation fails to achieve long-run social optimality.
Hamilton, Stephen F.
core   +1 more source

Socioenvironmental implications of Jatropha curcas cultivation for biodiesel supply in postmining communities

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The long‐term viability of Jatropha curcas as a biodiesel feedstock has been widely debated. Many early initiatives failed to deliver consistent economic returns despite promising environmental attributes. This study re‐evaluated J. curcas‐based systems within an integrated environmental–economic framework, focusing on their potential role in ...
Eduardo Sansão Sozinho Maurício   +3 more
wiley   +1 more source

Is the Food and Drug Administration Safe and Effective? [PDF]

open access: yes
In the United States, drug safety and efficacy are primarily regulated by the Food and Drug Administration (FDA) and the legal system, which gives manufacturers large incentives to produce safe drugs and provide proper warnings for side effects, since ...
Eric Sun, Tomas J. Philipson
core  

Low‐intervention clinical trials in Spain: Do they progress?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza   +4 more
wiley   +1 more source

Mandatory Versus Voluntary Disclosure of Product Risks [PDF]

open access: yes
We analyze a model in which firms are able to acquire information about product risks and may or may not be required to disclose this information. We initially study the effect of disclosure rules assuming that firms are not liable for the harm caused by
A. Mitchell Polinsky, Steven Shavell
core  

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

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