Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Carbon footprint analysis and carbon neutrality potential of desalination by reverse osmosis for different applications basd on life cycle assessment method. [PDF]
Zhang M, Yu S, Shi C, Wang H, Chang N.
europepmc +1 more source
Product and Process Innovation supported by Risk assessment, Life cycle costing and Life cycle assessment [PDF]
Duijm, Nijs Jan, Markert, Frank
core
Intercompartmental communication in senescence
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Resource Recovery from High-Performance Textile Waste: Carbon Footprint Assessment, Graded Recycling, and Product Development Pathway for Used Firefighting Protective Clothing. [PDF]
Zhang X +8 more
europepmc +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Advancing Sustainability in Hydrocarbon Production: Breakthroughs in CO<sub>2</sub> Hydrogenation with Iron-Based Catalysts and Comprehensive Life Cycle Assessment of Environmental Impacts. [PDF]
Grainca A +5 more
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Endowing plants with a dual-cycle heart to boost CO<sub>2</sub> fixation. [PDF]
Zhao C, Hao W, Chen X.
europepmc +1 more source

