Results 41 to 50 of about 1,806,355 (304)

Sustainability in the product design: A review of recent development based on LCA [PDF]

open access: yes, 2018
In order to achieve sustainable product design process, aspects such of environmental, economic and social should be balanced. This paper discussed on sustainability of product design, conceptual basis of life cycle assessment (LCA), review of LCA at ...
Hassan, Mohd Fahrul   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Adaptation of corporate model of ukrainian aircraft product life cycle to the international methodology of systems engineering

open access: yesMechanics and Advanced Technologies, 2023
Problems. Under the present-day conditions, the preservation of competences of Ukrainian aircraft construction enterprises will be determined by the possibility of enterprises attracting to participation in international cooperation programs and ...
Svitlana Kryvova   +2 more
doaj   +1 more source

Supply chain implications of sustainable design strategies for electronics products [PDF]

open access: yes, 2012
Increasing legislative and consumer pressures on manufacturers to improve sustainability necessitates that manufacturers consider the overall life cycle and not be scope restricted in creating products.
Bateman, RJ, De Coster, R, Plant, AVC
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Environmental Performance of Kettle Production: Product Life Cycle Assessment

open access: yesManagement Systems in Production Engineering, 2017
The main objective of this paper is to compare the environmental impact caused by two different types of water boiling processes. The aim was achieved thanks to product life cycle assessment (LCA) conducted for stovetop and electric kettles. A literature
Marcinkowski Andrzej, Zych Krzysztof
doaj   +1 more source

Environmental scenario as approach for achieving sustainability in product design

open access: yesJournal of Architecture, Art & Humanistic Science, 2019
Scenario is one of the most effective design tools and methods used to predict areas of success and failure in product design, it gives predictions about the life cycle and trajectory of the product during each stage, as the scenario is a futuristic tool
Osama Mohamed
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Blockchain-enabled product life cycle assessment information management system

open access: yesAin Shams Engineering Journal
Life Cycle Assessment (LCA) often faces challenges such as low data transparency, limited traceability, and poor data sharing among entities. To address these issues, this study develops a blockchain based life cycle information management system that ...
Jun Zhou, Yajun Duan
doaj   +1 more source

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