Results 81 to 90 of about 2,636,574 (342)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Product life cycle: the evolution of a paradigm and literature review from 1950-2009 [PDF]
, 2015 Copyright © 2012 Taylor & Francis. This is an Accepted Manuscript of an article published by Taylor & Francis in Production Planning & Control: The Management of Operations on 17 June 2011 (online), available online: http://www.tandfonline.com/10.1080 ...
Cao, Hui, Folan, Paul
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The product life cycle of durable goods [PDF]
The model presented here derives the product life cycle of durable goods. It is based on the idea that the purchase process consists of first purchase and repurchase.
Kaldasch, Joachim
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Vietnam Journal of Science, Technology and Engineering, 2017 Currently, there are various standards and guidelines to calculate product carbon footprints in the world such as the Greenhouse Gas (GHG) Protocol of the World Resources Institute/World Business Council for Sustainable Development (WRI/WBCSD), ISO ...
Minh Trang Dao, Thi Lan Huong Huynh
doaj +1 more source
Comparative life cycle assessment of LED lighting products [PDF]
, 2017 LED lighting products used in lighting applications and their subsequent environmental impact are growing rapidly. However, there are no in-depth updated studies that show how to assess and compare them for eco-design purposes.
Bare JC +13 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Erratum to: Life Cycle Assessment of Heaven Mushroom Product [PDF]
E3S Web of Conferences, 2021 Sukkanta Phatcharapron +1 more
doaj +1 more source
Product Life Cycle Planning [PDF]
, 2003 Abstract : Regional Sediment Management (RSM) refers to the effective use of littoral, estuarine, and riverine sediment resources in an environ-mentally effective and economical manner. The U.S. Army Corps of Engineers manages lands and waterways across the United States.
William J. Wolfe +6 more
openaire +1 more source