Results 31 to 40 of about 364,908 (245)

A causal multifractal stochastic equation and its statistical properties

open access: yes, 2003
Multiplicative cascades have been introduced in turbulence to generate random or deterministic fields having intermittent values and long-range power-law correlations. Generally this is done using discrete construction rules leading to discrete cascades.
Schmitt, Francois G.
core   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Poissonian and non Poissonian Voronoi Diagrams with application to the aggregation of molecules

open access: yes, 2009
The distributions that regulate the spatial domains of the Poissonian Voronoi Diagrams are discussed adopting the sum of gamma variate of argument two. The distributions that arise from the product and quotient of two gamma variates of argument two are ...
Abramowitz   +30 more
core   +1 more source

Approximation to Distribution of Product of Random Variables Using Orthogonal Polynomials for Lognormal Density [PDF]

open access: yes, 2012
We derive a closed-form expression for the orthogonal polynomials associated with the general lognormal density. The result can be utilized to construct easily computable approximations for probability density function of a product of random variables ...
Hämäläinen, Jyri   +3 more
core   +2 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A Method for the Combination of Stochastic Time Varying Load Effects [PDF]

open access: yes, 1983
The problem of evaluating the probability that a structure becomes unsafe under a combination of loads, over a given time period, is addressed. The loads and load effects are modeled as either pulse (static problem) processes with random occurrence ...
Pearce, H.T., Wen, Y.K.
core  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Analysis of binary spatial data by quasi-likelihood estimating equations

open access: yes, 2005
The goal of this paper is to describe the application of quasi-likelihood estimating equations for spatially correlated binary data. In this paper, a logistic function is used to model the marginal probability of binary responses in terms of parameters ...
Clayton, Murray K., Lin, Pei-Sheng
core   +1 more source

Craig's XY distribution and the statistics of Lagrangian power in two-dimensional turbulence [PDF]

open access: yes, 2008
We examine the probability distribution function (PDF) of the energy injection rate (power) in numerical simulations of stationary two-dimensional (2D) turbulence in the Lagrangian frame.
Bandi, Mahesh M., Connaughton, Colm
core   +2 more sources

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