Results 271 to 280 of about 578,139 (333)

Opinion of the Commission pursuant to Article 189 b(2)(d) of the EC Treaty, on the European Parliament’s amendments to the Council’s common position regarding the proposal for a European Parliament and Council Directive on connected telecommunications equipment and the mutual recognition of the conformity of equipment. Amending the proposal of the Commission. COM (98) 692 final, 15 December 1998 [PDF]

, 1998

core  

NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression

Advanced Science, EarlyView.
NUDT21 is overexpressed in colorectal cancer tumors and promotes colorectal cancer progression. NUDT21 promotes the production of a cyclin‐dependent kinase 19 (CDK19) mRNA isoform with a long 3′ UTR, which enhances cytoplasmic export and translation. Truncation of the CDK19 long 3′ UTR phenocopies NUDT21 loss, recapitulating the defects in cholesterol ...
Yeping Yu, Jixin Ma, Minwei Zhou, Xiaodong Gu, Yiming Zhou, Zhenyang Li, Tianyu Zhang, Wei Gong, Chuanxin Huang, Jianbin Xiang   +9 more
wiley   +1 more source

Correction: Socioeconomic and health disparities in adults diagnosed with type 1 diabetes mellitus before age 18: insights from the Italian PASSI surveillance system. [PDF]

Front Public Health
Zamagni G, Minardi V, Masocco M, Asta F, Candido R, Tornese G, Bresciani G, Manfredini V, Frattolin E, Carletti CV, Germano D, Maurel E, Ronfani L, Monasta L.   +13 more
europepmc   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Adverse events following measles, mumps, rubella and varicella virus vaccine live (PROQUAD^®) reported to the vaccine adverse event reporting system (VAERS), 2015-2025. [PDF]

Virol J
Liang G, Liu Q, Song Y.
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Measuring commercial cannabis availability: findings from a multi-state surveillance study in the US. [PDF]

Health Aff Sch
Nargis N, Asare S, Westmaas JL.
europepmc   +1 more source

Variability in addictive and carcinogenic potential of smokeless tobacco products marketed in Mumbai, India: a surveillance study

Sampada S. Nikam, Vikram Gota, Prakash Chandra Gupta, Namrata Puntambekar, Arjun Singh, Pankaj Chaturvedi, Peter W. Villalta, Dorothy K. Hatsukami, Jasjit S. Ahluwalia, Saonli Basu, Samir S. Khariwala, Irina Stepanov   +11 more
openalex   +1 more source

Consumer policy in the United Kingdom as compared with the other Member States of the European Union. XXIV (98) UK.2, 5 May 1998 [PDF]

, 1998

core  

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source