Results 31 to 40 of about 176,998 (309)

Postmarket surveillance: a review on key aspects and measures on the effective functioning in the context of the United Kingdom and Canada

open access: yesTherapeutic Advances in Drug Safety, 2019
Regulatory approvals for the marketing of medicinal products authorize medical practitioners to prescribe drugs to a group of patients that are defined within the license of the medicinal product.
Nikhil Raj   +5 more
doaj   +1 more source

Extending the utility of the WHO recommended assay for direct detection of enteroviruses from clinical specimen for resolving poliovirus co-infection

open access: yesBMC Research Notes, 2018
Objectives In a polio-free world there might be reduced funding for poliovirus surveillance. There is therefore the need to ensure that enterovirologist globally, especially those outside the global polio laboratory network, can participate in poliovirus
Temitope Oluwasegun Cephas Faleye   +8 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Occurrence of Pulmonary Oil Microembolism After Testosterone Undecanoate Injection: A Postmarketing Safety Analysis

open access: yesSexual Medicine, 2020
Background: The Aveed Risk Evaluation and Mitigation Strategy program was instituted because of potential risk of pulmonary oil microembolism (POME) and/or anaphylaxis after intramuscular injection of Aveed (testosterone undecanoate), indicated for ...
Alexander W. Pastuszak, MD, PhD   +2 more
doaj   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak   +15 more
wiley   +1 more source

Fluoride content of bottled water commercialized in two cities of northeastern Brazil

open access: yesBrazilian Journal of Oral Sciences, 2015
Aim: The objectives of this study were to evaluate the fluoride content of bottled water commercialized in two cities of northeastern Brazil and to compare the fluoride values measured in the water to the ones printed on the bottle label, considering ...
Consuelo Fernanda Macedo de Souza   +3 more
doaj   +1 more source

The safety assessment of tampons: illustration of a comprehensive approach for four different products

open access: yesFrontiers in Reproductive Health, 2023
IntroductionWe illustrate a comprehensive tampon safety assessment approach that assures products can be used safely. Material biocompatibility, vaginal mucosa assessment, vaginal microbiome evaluation, and in vitro assessment of potential risk of ...
Anne E. Hochwalt   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Serology for trachoma surveillance after cessation of mass drug administration. [PDF]

open access: yes, 2015
BACKGROUND: Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness worldwide. Yearly azithromycin mass drug administration (MDA) plays a central role in efforts to eliminate blinding trachoma as a public health ...
William Makupa   +41 more
core   +1 more source

Robust Maritime Target Detector in Short Dwell Time

open access: yesRemote Sensing, 2021
Detection of small-sized maritime targets is an important task for a marine surveillance radar. Recently, with the emergence of a marine surveillance radar system that has a narrow azimuth beamwidth and rapidly rotating antennas, the available dwell time
Myung-Jun Lee   +3 more
doaj   +1 more source

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