Results 61 to 70 of about 578,139 (333)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Illegal, Unreported and Unregulated (IUU) Fishing: A Whitepaper [PDF]

, 2015
Illegal, unregulated and unreported (IUU) fishing refers to fishing activities that do not comply with regional, national, or international fisheries conservation or management measures.
Bernd Cordes
core  

A generative-oriented model-driven design environment for customizable video surveillance systems [PDF]

, 2012
To tackle the growing complexity and huge demand for tailored domestic video surveillance systems along with a high demanding time-to-market expectation, engineers at IVV Automação, LDAa are exploiting video surveillance domain as families of systems ...
A Kleppe, Adriano Tavares, D Abrahams, D Lohmann, I Ahmad, I McRitchie, Jorge Cabral, José Mendes, João Monteiro, João Vale, K Czarnecki, K Czarnecki, K Czarnecki, K Kang, L Marcenaro, M Acher, MD Pesce, Mongkol Ekpanyapong, Nuno Cardoso, Paulo Cardoso, Paulo Garcia, Pedro Rodrigues, PL Plauger, R Anisko, T Buchmann, V Cechticky, V Sarinho, Y Hongyu   +27 more
core   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Infant product‐related injuries: comparing specialised injury surveillance and routine emergency department data

Australian and New Zealand Journal of Public Health, 2016
Objective: To explore the potential for using a basic text search of routine emergency department data to identify product‐related injury in infants and to compare the patterns from routine ED data and specialised injury surveillance data.
Kirsten Vallmuur, Ruth Barker
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

How can real‐world evidence aid decision making during the life cycle of nonprescription medicines?

Clinical and Translational Science, 2022
Real‐world evidence (RWE) is an emerging scientific discipline which is being increasingly utilized for decision making on prescription‐only medicines.
Emese Csoke, Sabine Landes, Matthew J. Francis, Larry Ma, Denise Teotico Pohlhaus, Christelle Anquez‐Traxler   +5 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Food and farm products surveillance

, 1995
This section of the 1994 Hanford Site Environmental Report summarizes the radiological analyses performed on food and farm samples collected during 1994. The food and farm sampling design addresses the potential influence of Hanford Site releases. Details of the sampling design and radionuclides analyzed are included in this section.
openaire   +2 more sources

The European Regulatory Framework and its implementation in influencing organic inspection and certification systems in the EU [PDF]

, 2010
The report presents a review of the most important European and international legislation that set the framework for organic certification, of reports prepared by international agencies working with organic standard setting and certification, and of ...
Belliere, Samanta Rosie, Compagnioni, Antonio, Huber, Beate, Jespersen, Lizzie Melby, Meinshausen, Florentine, Padel, Susanne, Puliga, Alessandro, Rüegg, Elisabeth, Stolze, Matthias, Vine, Jane   +9 more
core