Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
VISUALIZATION OF SPECIAL VEHICLE DUMMY BODY PARTS WITH THREE DIMENSIONAL PRINTER TECHNIQUES [PDF]
PT. Pindad Persero is a military manufacturing industry specialized vehicle division that uses three-dimensional printer techniques, in each design to accelerate the form of a prototype product development.
Adiluhung, H. (Hardy ) +1 more
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Writing instruction throughout the curriculum Writing instruction throughout the curriculum
During the past 25 years, Rhetoric and Composition Studies have joined together to create an interdisciplinary field whose theory and research have transformed our understanding of writing.
Betty Bamberg
doaj +2 more sources
Learning to Write and Writing to Write: Composition Instruction from Habit Formation to Cognition
Over the last fifty years or thereabouts, there has been an upsurge in SL/FL rhetoric studies that have given rise to a panoply of theories and approaches that have contributed and still contribute to a better teaching and learning of writing.
Amin Kebieche
doaj
Act 35, New School Performance Ratings, and School Choice [PDF]
Act 35 was a product of the Lakeview v Huckabee case and the related Extraordinary Legislative Session. The law § 6-15-2101 of the Arkansas code required the establishment of three school ratings: a rating of the school’s current academic performance (or
Jensen, Nathan C., Ritter, Gary W.
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Developing writing materials based on CTL approach for Indonesian EFL learners
This study aims at developing writing materials based on Contextual Teaching and Learning (CTL) approach for Indonesian EFL learners. It adapted R and D development model proposed by Borg and Gall consisting of seven steps: research and information ...
Sri Wahyuni
doaj +1 more source
Model Penilaian Sebaya Untuk Meningkatkan Hasil Pembelajaran Menulis Di SMP [PDF]
: Peer-Assessment Model to Improve the Writing Ability of Junior-High-School Students. This study is aimed at developing a peer-assessment (PA) model to improve the writing ability of junior-high-school students.
Basuki, I. A. (Imam)
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

