Results 201 to 210 of about 8,361,536 (279)

The MD3M Questionnaire: Assessing Master Data Management Maturity

, 2014
Software Production, Spruit, Marco, Pietzka, Katharina, Sub Software Production   +3 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A fixed methane filter maximizes freshwater emissions under warming. [PDF]

Nat Clim Chang
Harpenslager SF, Randall K, Zhu Y, Jackson MC, Sanders I, Gallo B, Harris D, Prentice H, Bespalaya YV, Aksenova OV, Milner A, Cameron TC, McKew BA, O'Gorman EJ, Yvon-Durocher G, Friberg N, Purdy KJ, Woodward G, Dumbrell AJ, Trimmer M.   +19 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Increased hydrogen and ethanol production in transformants of the filamentous cyanobacterium Phormidium lacuna. [PDF]

Arch Microbiol
Spohrer N, Reinicke F, Malik S, Tarakji R, Weber N, Lamparter T.   +5 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Beyond petrochemicals: challenges and opportunities in industrial-scale biomanufacturing. [PDF]

Nat Commun
Kim JY, Yu HE, Kim MH, Lee SY.
europepmc   +1 more source

Identifying Companies in Open Source Software Ecosystems

, 2015
Software Production, Jansen, R.L., Buis, Jakob, Sub Software Production   +3 more
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

In vitro digestibility and ruminal methane production of the predominant Namibian rangeland encroacher bush species collected in two different seasons. [PDF]

Trop Anim Health Prod
Lugambo SK, Johnfisher M, Emmanuel L, Anni HB, Aila V.   +4 more
europepmc   +1 more source