Results 51 to 60 of about 2,727,265 (265)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Simulation Based Performance Assessment of Developing Heterarchical Control for a Flexible Assembly System

open access: yesManagement Systems in Production Engineering
In order to increase the robustness and flexibility of manufacturing systems under dynamic conditions which represented by disturbances that caused by uncertainties in customer demand, the heterarchical control multiagents’ system is increasingly being ...
Ismayyir Dhuha Kadhim   +2 more
doaj   +1 more source

Phenotypic and molecular characterization of Hessian fly resistance in diploid wheat, Aegilops tauschii

open access: yesBMC Plant Biology, 2019
Background The Hessian fly (Mayetiola destructor), belonging to the gall midge family (Cecidomyiidae), is a devastating pest of wheat (Triticum aestivum) causing significant yield losses.
Jill A. Nemacheck   +3 more
doaj   +1 more source

PHYLOGENETIC AND HISTOPATHOLOGICAL CHARACTERIZATION OF NEWCASTLE DISEASE VIRUSES REVEALS HIGH PREVALENCE OF VERY VIRULENT STRAINS OF GENOTYPE VIID IN EGYPT [PDF]

open access: yesAssiut Veterinary Medical Journal, 2016
Newcastle disease virus (NDV) is a highly contagious disease in poultry, also considered as a major challenge for the commercial and traditional poultry industry in Egypt. In this study clinicopathological and immunohistochemistry examination of fourteen
NAGLAA HAGAG   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

GENETIC CHARACTERISTICS OF INFECTIOUS BURSAL DISEASE VIRUS IN EGYPT FROM 2012 TO 2014 [PDF]

open access: yesAssiut Veterinary Medical Journal, 2015
The infectious bursal disease virus (IBDV) is a continuing serious problem facing poultry industry in Egypt.  In this study, 24 bursae samples collected from different broiler flocks (from Giza, Dakahleya, Ismailia, Damietta and Alexanderia) experiencing
NAGLAA HAGAG   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Novel Autonomous Robotic Vehicle-Based System for Real-Time Production and Safety Control in Industrial Environments

open access: yesComputers
Industry 4.0 has revolutionized the way companies manufacture, improve, and distribute their products through the use of new technologies, such as artificial intelligence, robotics, and machine learning.
Athanasios Sidiropoulos   +16 more
doaj   +1 more source

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