Results 41 to 50 of about 7,946,576 (307)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Economic nitrogen rate for fertigation of green corn crop in the Brazilian semiarid [PDF]
: The objective of this work was to determine the nitrogen rate for fertigation associated with the maximum productivity of green corn (Zea mays) with a lower production cost, in two harvest seasons in the Brazilian semiarid region.
Ênio Gomes Flôr Souza +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
ANALYTICAL STUDY OF THE DETERMINANTS OF PRODUCTION AND COST FUNCTIONS OF ONION SANDY LANDS, BENI SUEF GOVERNORATE [PDF]
Productivity efficiency is defined as a measure of the efficiency or efficiency of a particular production component of the production component when used with other elements.
Mohamed Osman +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Increased interest in marine fish farming in the United States has led to a need for fundamental economic information on production of candidate species for commercialization in various production systems.
Carole Ruth Engle +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Analysis of factors affecting the prediction of future saffron prices on the Iranian Commodity Exchange [PDF]
The aim of the present study is to analyze the factors affecting the forecast of future prices of saffron in the Iranian Commodity Exchange. This research is applicable in terms of its purpose, and post-event in terms of its nature.
Souad Ramezani vanegah +2 more
doaj +1 more source

