Results 91 to 100 of about 22,034,699 (325)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Measuring the economic efficiency of Italian agricultural enterprises [PDF]
Early microeconomic theory established its framework under the assumption that producers’ behaviour is optimal towards input allocation and output level. Since Debreu and Farrell this basic neoclassical approach has been extended, allowing for producers’
Darina Zaimova
core
Vector boson and charmonia measurements in $p$+Pb collisions with ATLAS
, 2016 The production of electroweak bosons ($Z,\gamma$ and $W$) and charmonia is sensitive to the initial-state geometry of heavy-ion collisions and to the parton distribution function with its potential nuclear modification.
Koehler, Markus K.
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Factors influencing the economics of the pork meat production
Agricultural Economics (AGRICECON), 2011 The research of the influence of the relevant factors and their interrelations on the economics of the pork meat production on a farm has been carried out with the help of the method of production functions (factor - product and factor - factor).
Jovan BABOVIĆ +3 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Estimating a Production Function for Iran with Emphasis on Energy and Expenditure on Research and Development: An Application of Genetic Algorithm Method [PDF]
پژوهشهای اقتصادی, 2016 This paper aims to estimate various production functions, with emphasis on energy and investment in R& D, in Iran over the period 1979-2010. Following estimation of different production functions including CES (Constant Elasticity of Substitution), GPF ...
Karim Eslamloueyan, Ali Hussain Ostadzad
doaj
SELECTING FUNCTIONAL FORM IN PRODUCTION FUNCTION ANALYSIS [PDF]
Functional form selection is a sometimes neglected aspect of applied research in production analysis. To provide an improved and uniform basis for form selection, a number of traditional and popular functional forms are catalogued with respect to ...
Griffin, Ronald C. +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source