Results 121 to 130 of about 13,186,845 (314)

Digitalization as a Factor of Production in China and the Impact on Total Factor Productivity (TFP)

Systems
In the digital transformation era, digitalization integrates deeply into production, bolstering output efficiency and economic value. Through stochastic frontier analysis (SFA), this research positions digitalization as an input in the production ...
Pei Li, Jinyi Liu, Xiangyi Lu, Yao Xie, Ziguo Wang   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

SELECTING FUNCTIONAL FORM IN PRODUCTION FUNCTION ANALYSIS [PDF]

Functional form selection is a sometimes neglected aspect of applied research in production analysis. To provide an improved and uniform basis for form selection, a number of traditional and popular functional forms are catalogued with respect to ...
Rister, M. Edward, Montgomery, John M., Griffin, Ronald C.   +2 more
core  

When can physical distancing be relaxed? A health production function approach for COVID-19 control policy. [PDF]

BMC Public Health, 2021
Wibowo DH.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

STOCHASTIC FRONTIER ANALYSIS OF PRODUCTION FUNCTION AND COST FUNCTION ESTIMATION METHODS. STUDY OF EFFICIENCY AT INDUSTRY LEVEL [PDF]

This paper analyses the efficiency or productivity at the level of a production unit, but also at industry level, resorting for this purpose to both parametric and non-parametric techniques.
Iulian LIŢĂ, Tănase STAMULE
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Estimating the production function of university students [PDF]

This paper estimates the production function for university students in English universities. Taking as the output the quality of a university degree and the dropout rate, we use as inputs teaching quality and quantity, entry qualifications, and the ...
K T Soo
core