Results 151 to 160 of about 20,186,890 (357)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Cotton Farmers' Technical Efficiency: Stochastic and Nonstochastic Production Function Approaches
Technical efficiency for cotton growers is examined using both stochastic (SFA) and nonstochastic (DEA) production function approaches. The empirical application uses farm-level data from four counties in west Texas.
Chakraborty, Kalyan +2 more
core +1 more source
, 2019 Comparison of the contribution rates calculated by the CES production function and the Cobb-Douglas production function.
Long Tan (4279273) +9 more
core +1 more source
Macroeconomics of destructiveness: Determinants behind social systems’ development
Journal of New EconomyThe macroeconomic concept of human stupidity proposed by Carlo Cipolla in 1976 allows assessing the impact of a group of people with destructive behaviour on the trajectory of economic growth.
Evgeny V. Balatsky
doaj +1 more source
Nonparametric estimation of a primary care production function in urban Brazil. [PDF]
Health Econ Rev, 2020 Wichmann B, Wichmann R.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the estimation of technical inefficiency in the stochastic frontier production function model
, 1982 J. Jondrow +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Identification Properties of Recent Production Function Estimators
, 2015 Daniel A. Ackerberg +2 more
semanticscholar +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source