Results 211 to 220 of about 13,118,916 (332)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli. [PDF]

PLoS Biol, 2019
Cummings M, Peters AD, Whitehead GFS, Menon BRK, Micklefield J, Webb SJ, Takano E.   +6 more
europepmc   +1 more source

Design of a High-Speed Intelligent Production Line for Medical Protective Garments

Yanhua Liu, Gaoqing He, Junlin Pan, Xuexiang Cao   +3 more
openalex   +1 more source

A new hybrid Sustainable Lean Six Sigma framework to improve production line performance [PDF]

Dana Marsetiya Utama, Ardhalena Ragil Putri Kinanti, Shanty Kusuma Dewi, Danang Setiya Wijaya   +3 more
openalex   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Task Scheduling Based on a Hybrid Heuristic Algorithm for Smart Production Line with Fog Computing. [PDF]

Sensors (Basel), 2019
Wang J, Li D.
europepmc   +1 more source

Capacity Expansion and the Capability–Defect Gap After Automating a Screw-Fastening Station: A Lean Six Sigma DMAIC Case Study in an Automotive Safety-Components Production Line

Eduarda Teixeira, António Rocha, Filipe J.P. Chaves   +2 more
openalex   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Turning nature's inspiration into a production line. [PDF]

EMBO Rep, 2014
Hunter P.
europepmc   +1 more source

Agent based Scheduling of Production Line [PDF]

Carlos Filipe Ramos de Sousa
openalex