Results 101 to 110 of about 5,567,138 (311)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Methodology Of Assessing Investment Attractiveness Of Ukrainian Gas Producers [PDF]

, 2018
The development of a methodology for assessing investment attractiveness of businesses of Ukrainian gas production industry that is presented in the form of a generalized algorithm reflects the conceptual model of research.
Pysar, N. (Nadiia)
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Does a Lack of Early Intensive Socialisation with Humans Exclude Goats from Participating in Animal-Assisted Services?

Animals
Socialisation with humans and willingness to interact with them are essential traits for animals involved in animal-assisted services (AAS). This study examined whether goats without prior intensive socialisation with humans may show predispositions to ...
Wiktoria Janicka, Kamila Janicka, Patrycja Magdalena Masier, Agnieszka Ziemiańska, Iwona Rozempolska-Rucińska   +4 more
doaj   +1 more source

The simulation model of the grapple loader operation

MATEC Web of Conferences, 2019
The main objective of the study was to develop a simulation model for the operation of the T-214 CYKLOP grapple loader using the MATLAB package. The created model allowed assessment of the behaviour of the real object in the operating conditions under ...
Tucki Karol, Bączyk Anna, Mruk Remigiusz, Wielewska Izabela, Radziszewski Piotr   +4 more
doaj   +1 more source

Biogas quality and nutrient remediation in palm oil mill effluent through Chlorella vulgaris cultivation using a photobioreactor [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: During this energy transition, research is being done to develop sustainable ways to support the shift to a decarbonized energy and production system.
T. Handayani, I.N. Djarot, N. Widyastuti, F.D. Arianti, A. Rifai, A.I. Sitomurni, M.M.A. Nur, R.N. Dewi, N. Nuha, J. Haryanti, D. Pinardi, Y. Suryana, A. Aziz, E. Syamsudin, T. Rochmadi, P.A. Lomak, A. Hadi, M.D. Pertiwi, E. Yuniastuti, N.A. Putri   +19 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The environmental and health impacts of tobacco agriculture, cigarette manufacture and consumption. [PDF]

, 2015
The health consequences of tobacco use are well known, but less recognized are the significant environmental impacts of tobacco production and use.
Bialous, Stella Aguinaga, Burt, Lindsay, Curtis, Clifton, da Costa, Vera Luiza, Iqtidar, Silvae Usman, Liu, Yuchen, Novotny, Thomas E, Pujari, Sameer, Tursan d'Espaignet, Edouard   +8 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Characterization of the Coding Sequence of the MC1R (Melanocortin 1 Receptor) Gene of Ayam Cemani Black Chickens

Animals
Plumage color is one of the most important traits characterizing chicken breeds. Black-boned chickens constitute a specific group of breeds with a unique phenotype. One of the representatives is the Indonesian Ayam Cemani.
Beata Horecka, Witold Wojciechowski, Kamil Drabik, Karolina Wengerska, Justyna Batkowska   +4 more
doaj   +1 more source