Results 131 to 140 of about 20,614,141 (350)

A Make-to-Order Capacitated Lot-Sizing Model with Parallel Machines, Eligibility Constraints, Extra Shifts, and Backorders

Mathematics
This study addresses the multi-period, multi-item, single-stage capacitated lot sizing problem (CLSP) in a parallel machine environment with machine eligibility constraints under a make-to-order production policy. A mixed-integer linear programming (MILP)
Felipe T. Muñoz, Juan Ulloa-Navarro
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Journey to 2030 : transportation plan of the Boston region metropolitan planning organization. [PDF]

3C PL Contract #48696MA-80-0001JOURNEY to 2030, the Transportation Plan of the Boston Region Metropolitan Planning Organization (referred to as the Plan), is the long-range, comprehensive transportation planning document for the Boston region. The region
Metropolitan Planning Organization (Mass.). Central Transportation Planning Staff
core  

Progress report, Nemaha County Planning Board

, 1938
"August, 1938.", Reproduced from typewritten copy.; "First of a series of publications which will be issued from time to time on subdivisional planning."--Foreword.Nemaha County Planning Board -- Foreword -- Table Of Contents -- Introduction -- General ...
Nemaha County Planning Board (Kan.)
core   +1 more source

Enhancing Production Efficiency Through Digital Twin Simulation Scheduling

Applied Sciences
Flexible custom manufacturing is becoming increasingly important, and, in the near future, it will serve as a key method to counter growing competition and meet market demands across most industrial sectors.
Patrik Grznár, Ladislav Papánek, Milan Marčan, Martin Krajčovič, Ivan Antoniuk, Štefan Mozol, Lucia Mozolová   +6 more
doaj   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Principles of planning

The nature of planning. Essentials of planning. Comprehensive program of planning. Planning process.
Peng, George T. C.
core   +1 more source

Machine learning applied in production planning and control: a state-of-the-art in the era of industry 4.0

Journal of Intelligent Manufacturing, 2020
Juan Pablo Usuga Cadavid, S. Lamouri, B. Grabot, R. Pellerin, Arnaud Fortin   +4 more
semanticscholar   +1 more source

Optimal Solutions of Economic Lot Scheduling Problem with Energy and Power Costs

Energies
This paper proposes a new planning method for a cyclic production of many different products with steady demand and variable production rates, which minimises energy consumption while reducing and equalising power demand.
Waldemar Kaczmarczyk
doaj   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

FEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille, Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Luiz Lehmann Coutinho, Carlos Guerrero‐Bosagna   +6 more
wiley   +1 more source