Results 61 to 70 of about 1,696,962 (296)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Can Differentiated Production Planning and Control enable both Responsiveness and Efficiency in Food Production?

open access: yesInternational Journal on Food System Dynamics, 2014
This paper addresses the complex production planning and control (PPC) challenges in food supply chains. The study illustrates how food producers' traditional make‐to‐stock (MTS) approach is not well suited to meet the trends of increasing product ...
Anita Romsdal   +2 more
doaj  

The Last Planner® System and Building Information Modeling in Construction Execution: From an Integrative Review to a Conceptual Model for Integration

open access: yesApplied Sciences, 2020
Many researchers have stated that lean and building information modeling (BIM) have positive synergies. This integrative literature review aims at exploring this body of knowledge within the scope of combinations of BIM and the Last Planner® System,
Christoph Paul Schimanski   +3 more
doaj   +1 more source

Adaption of structured analysis design techniques methodology for construction project planning [PDF]

open access: yes, 2012
The construction industry has been heavily criticised by researchers and governmental organisations for its performance especially excessive delay. Ballard and Howell (2003) indicated that only about 50% of the tasks on weekly work plans are completed by
Agyekum-Mensah, G   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Production planning and control of closed-loop supply chains [PDF]

open access: yes
More and more supply chains emerge that include a return flow of materials. Many original equipment manufacturers are nowadays engaged in the remanufacturing business. In many process industries, production defectives and by-products are reworked.
Inderfurth, K., Teunter, R.H.
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Selecionando uma aplicação de Tecnologia da Informação com enfoque na eficácia: um estudo de caso de um sistema para PCP Selecting an Information Technology application through an effectiveness approach: a production planning system case study

open access: yesGestão & Produção, 2002
Ao longo dos anos, a Tecnologia da Informação (TI) vem de maneira crescente apoiando as atividades mais diretamente ligadas à produção. Sendo inicialmente suporte de tarefas mais simples, a TI passa a estar presente em todas as etapas do processo ...
Fernando José Barbin Laurindo   +3 more
doaj   +1 more source

Simulation-Based Multi-Criteria Optimization of Parallel Heat Treatment Furnaces at a Casting Manufacturer

open access: yesJournal of Manufacturing and Materials Processing, 2020
This paper presents the development and evaluation of a digital method for multi-criteria optimized production planning and control of production equipment in a case-study of an Austrian metal casting manufacturer.
Thomas Sobottka   +2 more
doaj   +1 more source

Production planning and control of closed-loop supply chains [PDF]

open access: yes, 2001
More and more supply chains emerge that include a return flow of materials. Many original equipment manufacturers are nowadays engaged in the remanufacturing business. In many process industries, production defectives and by-products are reworked. These
Inderfurth, K. (Karl)   +1 more
core  

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