Results 41 to 50 of about 776,427 (222)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Bi-objective Model for Mineral Supply Chain Network Design Considering Social Responsibility and solving by a Novel Fuzzy Multi-choice Goal Programming method [PDF]
International Journal of Industrial Engineering and Production Research, 2023 The main objective of this research is effective planning as well as greener production and distribution of mineral products in supply chain network.
Fatemeh Hajisoltani +2 more
doaj
A modular hybrid simulation framework for complex manufacturing system design [PDF]
, 2019 For complex manufacturing systems, the current hybrid Agent-Based Modelling and Discrete Event Simulation (ABM–DES) frameworks are limited to component and system levels of representation and present a degree of static complexity to study optimal ...
Erkoyuncu, J. A. +3 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Product Service System Innovation in the Smart City [PDF]
, 2018 Product service systems (PSS) may usefully form part of the mix of innovations necessary to move society toward more sustainable futures. However, despite such potential, PSS implementation is highly uneven and limited.
Aoun C +14 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Renewable and Sustainable Energy Reviews, 2023 Increased use of environmentally friendly and energy-efficient transportation, such as electric vehicles, results in increased demand for power supply, putting pressure on the electricity infrastructure. One of the key challenges facing power companies operating within this context is effectively planning power production across multiple production ...
Qiao Peng +4 more
openaire +3 more sources
AI and OR in management of operations: history and trends [PDF]
, 2007 The last decade has seen a considerable growth in the use of Artificial Intelligence (AI) for operations management with the aim of finding solutions to problems that are increasing in complexity and scale.
Kobbacy, KAH, Rasmy, MH, Vadera, S
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source