Results 51 to 60 of about 776,441 (307)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Prospects and Challenges of Green Hydrogen Economy via Multi-Sector Global Symbiosis in Qatar

open access: yesFrontiers in Sustainability, 2021
Low carbon hydrogen can be an excellent source of clean energy, which can combat global climate change and poor air quality. Hydrogen based economy can be a great opportunity for a country like Qatar to decarbonize its multiple sectors including ...
Fadwa Eljack, Monzure-Khoda Kazi
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Characteristics of developed flexible polyurethane foams reinforced with coconut coir fibres and recycled tyres [PDF]

open access: yes, 2012
Flexible Polyurethane (PU) foam is generally used in seat cushions of automotive seating for comfort and supporting the occupants. However, due to the demand for more comfortable compartment; seat cushions are now designed for better riding comfort
Chan, Wen Shan
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Organic Exporter Guide [PDF]

open access: yes, 2006
This guide was developed for the programme 'Export Promotion of Organic Products from Africa' (EPOPA), implemented by Agro Eco and Grolink. The focus of this guide is on export marketing of organic agricultural products.
Koekoek, F.J.
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Operational planning of WEF infrastructure: quantifying the value of information sharing and cooperation in the Eastern Nile basin

open access: yesEnvironmental Research Letters, 2021
Integrating the planning of a multi-reservoir system in nexus with agricultural and electricity infrastructure could alleviate security concerns for these resources in regions where demand is growing while water and land scarcity are exacerbated by ...
Jeroen Verhagen   +2 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Optimal Outsourcing Strategy Determination and Pricing Model in Dual-Channel Supply Chain under Uncertainty [PDF]

open access: yesمدیریت تولید و عملیات, 2019
In the past, traditional channel or retailer was used for selling products but with the development of e-commerce, a large company in the world considers another sale channel like websites. Considering the existence of two channels for sale, choosing the
Mahboobeh Honarvar, Hossein Rezaee
doaj   +1 more source

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