Results 51 to 60 of about 776,427 (222)

Prospects and Challenges of Green Hydrogen Economy via Multi-Sector Global Symbiosis in Qatar

open access: yesFrontiers in Sustainability, 2021
Low carbon hydrogen can be an excellent source of clean energy, which can combat global climate change and poor air quality. Hydrogen based economy can be a great opportunity for a country like Qatar to decarbonize its multiple sectors including ...
Fadwa Eljack, Monzure-Khoda Kazi
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Sensitivity of multi-product two-stage economic lotsizing models and their dependency on change-over and product cost ratio's [PDF]

open access: yes, 2010
This study considers the production and inventory management problem of a two-stage semi-process production system. In case both production stages are physically connected it is obvious that materials are forced to flow.
Aghezzaf, El-Houssaine   +2 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Re-reengineering the dream: agility as competitive adaptability [PDF]

open access: yes, 2014
Organizational adaptation and transformative change management in technology-based organizations is explored in the context of collaborative alliances.
Allan F. McLay
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Operational planning of WEF infrastructure: quantifying the value of information sharing and cooperation in the Eastern Nile basin

open access: yesEnvironmental Research Letters, 2021
Integrating the planning of a multi-reservoir system in nexus with agricultural and electricity infrastructure could alleviate security concerns for these resources in regions where demand is growing while water and land scarcity are exacerbated by ...
Jeroen Verhagen   +2 more
doaj   +1 more source

Organic Exporter Guide [PDF]

open access: yes, 2006
This guide was developed for the programme 'Export Promotion of Organic Products from Africa' (EPOPA), implemented by Agro Eco and Grolink. The focus of this guide is on export marketing of organic agricultural products.
Koekoek, F.J.
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Optimal Outsourcing Strategy Determination and Pricing Model in Dual-Channel Supply Chain under Uncertainty [PDF]

open access: yesمدیریت تولید و عملیات, 2019
In the past, traditional channel or retailer was used for selling products but with the development of e-commerce, a large company in the world considers another sale channel like websites. Considering the existence of two channels for sale, choosing the
Mahboobeh Honarvar, Hossein Rezaee
doaj   +1 more source

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