Results 51 to 60 of about 375,167 (310)

Integrated Production and Transportation Scheduling Method in Hybrid Flow Shop

open access: yesChinese Journal of Mechanical Engineering, 2022
The connection between production scheduling and transportation scheduling is getting closer in smart manufacturing system, and both of those problems are summarized as NP-hard problems.
Wangming Li   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Order scheduling optimization in manufacturing enterprises based on MDP and dynamic programming

open access: yesScientific Reports, 2023
In the era of Industry 4.0, order scheduling is a crucial link in the production of manufacturing enterprises. In view of order scheduling in manufacturing enterprises, a finite horizon Markov decision process model is proposed in this work based on two ...
Qiqige Wulan
doaj   +1 more source

Facility Layout Linked with Scheduling Problem by Genetic Algorithm and Tabu Search [PDF]

open access: yes, 1998
In this paper, we propose a method to solve simultaneously facility layout problem and scheduling problem. About a initial random layout planning, the production scheduling and the transportation scheduling of AGV are obtained by using priority rules ...
Fujihara, Yutaka, Osaki, Hirokazu
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Scheduling tirage champagne production [PDF]

open access: yes, 1991
Linear programming models for the scheduling of tirage champagne production are presented. The basic model demonstrates that cyclic schedules which reduce the average holdings of both maturation and finished product stock can be determined. Reduced costs
Panton, D.
core  

Power efficient job scheduling by predicting the impact of processor manufacturing variability [PDF]

open access: yes, 2019
Modern CPUs suffer from performance and power consumption variability due to the manufacturing process. As a result, systems that do not consider such variability caused by manufacturing issues lead to performance degradations and wasted power.
Casas, Marc   +5 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Hybrid Flow Shop Scheduling Problems Using Improved Fireworks Algorithm for Permutation

open access: yesApplied Sciences, 2020
Prior studies are lacking which address permutation flow shop scheduling problems and hybrid flow shop scheduling problems together to help firms find the optimized scheduling strategy.
Xuelian Pang   +4 more
doaj   +1 more source

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