Results 121 to 130 of about 10,538,298 (326)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Far from champions, close to midgets : international production sharing in Central and South America [PDF]
This paper assesses the relative participation of Argentina, Brazil, Guatemala and Nicaragua in fragmented world production. Based on trade statistics from 2000 to 2004, it analyses whether the trade flows of these economies have evolved towards ...
Calfat, Germán +3 more
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Social Welfare versus Inequality Concerns in an Incomplete Contract Experiment [PDF]
We study a situation where two players first choose a sharing rule, then invest into a joint production process, and then split joint benefits. We investigate how social preferences determine investments.
Helmut Rainer +2 more
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
THINKING GLOBALLY -- FARMING GLOBALLY [PDF]
The agriculture industry continues to adopt business practices based on strategic alliances. Generally these alliances emphasize vertical coordination wherein producers enter into long-term agreements with suppliers, processors, and businesses in other ...
Saxowsky, David M. +1 more
core +1 more source
Electricity Market Equilibrium under Information Asymmetry
, 2019 We study a competitive electricity market equilibrium with two trading stages, day-ahead and real-time. The welfare of each market agent is exposed to uncertainty (here from renewable energy production), while agent information on the probability ...
Dvorkin, Vladimir +2 more
core +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Risk-sharing and its role in manufacturer’s innovation
Production and Manufacturing Research: An Open Access JournalThis study seeks a more developed understanding of the nature of manufacturers’ risk-sharing relations with suppliers and customers and how these relations and the use of manufacturing technologies affect process and product innovation.
Gregory Theyel, Christopher Tucci
doaj +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source