Results 71 to 80 of about 847,146 (267)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Continuous production of California timber can yield profitable returns
Two types of landowner are affected by the emerging and increasing opportunities for the management of timber on a continuous basis as a permanent and profitable business—the industrial lumbermen and the farmer or other rural proprietor of a small tract ...
P Barr
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Silencing of GhSHP1 hindered flowering and boll cracking in upland cotton
The opening of cotton bolls is an important characteristic that influences the precocity of cotton. In the field, farmers often use chemical defoliants to induce cotton leaves to fall off earlier, thus accelerating the cracking of cotton bolls.
Wenjuan Xu +8 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Dynamics of lentil (Lens culinaris) production and trade: Global scenario and Indian interdependence
Increasing pulse production is one of the national priorities for food and nutritional security of India. In this context, incremental changes in pulse production can play a pivotal role.
UMA SAH +7 more
doaj +1 more source
Flagella disruption in Bacillus subtilis increases amylase production yield. [PDF]
Fehler AO +6 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The structure of production in Romanian agriculture - the gap between the EU27
The paper aims to capture the differences between the production structures of different countries and differences existing in some respects, between Romania and EU.
Radu Voicu +2 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

