Results 101 to 110 of about 266,637 (207)

Détermination des acides aminés limitants chez le taurillon BBBc recevant une ration à base d'ensilage de maïs [PDF]

open access: yes, 2003
peer ...
Bartiaux-Thill, Nicole   +3 more
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

L'évolution des méthodes de recherche-développement sur les systèmes d'élevage en régions chaudes [PDF]

open access: yes, 1994
L'auteur rappelle d'abord que les démarches de la zootechnie classique sont apparues mal adaptées aux spécificités des élevages des régions chaudes. Une "nouvelle démarche" a donc été proposée; ses fondements sont : un recentrage sur l'homme, acteur du ...
Lhoste, Philippe
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Evolutions des systèmes d'élevage bovin au nord-ouest du Bénin [PDF]

open access: yes, 2019
La grande variabilité des modes de conduite de l'activité d'élevage observée dans le bassin de la Donga au nord-ouest du Bénin, résultant du durcissement de la politique forestière et de l'intensification écologique, a permis de distinguer les deux ...
Houinato, Marcel   +5 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Bibliographie sur les systèmes de production: Burkina Faso, Mali, Niger [PDF]

open access: yes, 1993
Cette bibliographie répond à un des objectifs du sous-réseau "systèmes de production" du Réseau de la CORAF de Recherche sur la Résistance à la Sécheresse (R3S) qui est de fournir de l'information scientifique et technique à ses chercheurs en mobilisant ...
CCD R3S - FRA, CIRAD-CA - FRA
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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