Results 21 to 30 of about 2,133 (188)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Systèmes d'élevage en ferme : les zootechniciens européens à la recherche de concepts et d'outils [PDF]

open access: yes, 1994
Une série de symposiums FEZ (Fédération Européenne de Zootechnie)/CEE est organisée pour l'étude des systèmes d'élevage en ferme. Les démarches mises en oeuvre sont basées sur l'analyse de système et sur la modélisation systémique.
Flamant, Jean Claude   +5 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Système d'élevage et économie de la production caprine dans les zones traditionnelles du Zimbabwe. I. Les bâtiments d'élevage [PDF]

open access: yes, 1992
Dans le cadre de l'enquête nationale sur "la mortalité des chevreaux dans les zones communales du Zimbabwe", les caractéristiques de 219 bâtiments d'élevage, utilisés par les petits ruminants, ont été enregistrées et analysées.
Borne, Pierre Marie   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Le mini-élevage et la faune: 1983-2002 [PDF]

open access: yes, 2004
Minilivestock and Fauna: 1983-2002. The author makes a synthesis on the trend observed through the first twenty volumes of Tropicultura regarding papers on minilivestock and wild fauna.
Hardouin, J.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Contribution du Cirad-Emvt à l'appui scientifique du projet FSP "concertation agricole et structuration des filières en Ouganda" : rapport de mission en Ouganda du 15 au 22 mars 2003 [PDF]

open access: yes, 2003
Présent en Ouganda depuis 1998, le Programme Productions Animales (CIRAD-EMVT) n'avait pour l'instant oeuvré qu'au travers de missions courtes et d'appui à des stagiaires et un CSN. Le démarrage du FSP "concertation agricole et soutien aux filières (CASF)
Faye, Bernard, Grimaud, Patrice
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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