Le dromadaire et le cochon : deux visions opposées de l'élevage ? [PDF]
Le dromadaire et le cochon sont deux espèces d'élevage emblématiques d'un gradient allant de l'extensif à l'intensif et se déclinant sur divers registres a priori exclusifs. Pourtant, malgré les différences fondamentales de ces deux espèces, tant sur les
Faye, Bernard, Porphyre, Vincent
core +2 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Anthelmintic Activity, Cytotoxicity, and Phytochemical Screening of Plants Used to Treat Digestive Parasitosis of Small Ruminants in Benin (West Africa). [PDF]
Tchetan E +12 more
europepmc +1 more source
Un outil simple de projection démographique pour estimer la productivité d'un cheptel : application à un cheptel bovin de la zone cotonnière au Mali-Sud [PDF]
International audienceL'article présente une interface développée sous forme de feuilles de tableur, appelée Dynmod (http://livtools.cirad.fr), permettant de réaliser des projections démographiques de cheptel de ruminants et d'estimer leur productivité ...
Ba, Alassane +4 more
core +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Fractionation Coupled to Molecular Networking: Towards Identification of Anthelmintic Molecules in Terminalia leiocarpa (DC.) Baill. [PDF]
Tchetan E +8 more
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Incorporation of fresh leaves of wormwood (Artemisia herba alba) and/or rosemary (Rosmarinus officinalis) in the diet of rams: Effect on testicular function, sexual behavior, and blood parameters. [PDF]
Khnissi S +8 more
europepmc +1 more source
Le conseil en élevage en milieu tropical [PDF]
Les contraintes propres aux pays tropicaux (illétrisme, logiques non marchandes, contextes sociologiques, faiblesse de l'encadrement, pauvreté) et le rôle multiple de l'activité d'élevage (sécurisation, capitalisation, diversification, intégration ...
Faye, Bernard, Lhoste, Philippe
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

