Results 101 to 110 of about 1,354,863 (284)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Productive pedagogies : is it an intelligible language for preservice teachers?

open access: yes, 2003
Australian teacher educators and teachers have become increasingly familiar with the notion of ‘Productive Pedagogies’, itself the product of longitudinal research on school reform recently undertaken in Queensland, Australia (Lingard et al.,
Gale, Trevor, Zyngier, David
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Development of emotional knowledge and its relationship with productive vocabulary in monolingual and multilingual children in pre-primary classes

open access: yesJournal of Research in Social Sciences and Language
Emotional and language skills are prerequisites for successful participation in educational processes. Multilingual children often have different backgrounds for acquiring German, which can affect their language and emotional development.
Christin Büning   +6 more
doaj   +1 more source

The Impact of Trade on Intra-Industry Reallocations and Aggregate Industry Productivity [PDF]

open access: yes
This paper builds a dynamic industry model with heterogeneous firms that explains why international trade induces reallocations of resources among firms in an industry.
Mark J. Melitz
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Disseminating Knowledge Products [PDF]

open access: yes, 2017
Dissemination is the interactive process of communicating knowledge to target audiences so that it may be used to lead to change. The challenge is to improve the accessibility of desired knowledge products by those they are intended to reach. This means ensuring physical availability of the product to as large a proportion of the target audience as ...
openaire   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Working Memory Capacity, TL Grammar Attainment and Length of Study as Predictors of Explicit and Implicit (Automatized) Knowledge of English Passive Voice

open access: yesPsychology of Language and Communication
This study investigated the relationship between phonological short-term memory (PSTM), working memory capacity (WMC), and receptive and productive dimensions of explicit and implicit (automatized) knowledge of English passive voice, also taking into ...
Biedroń Adriana   +2 more
doaj   +2 more sources

Transformational learning experiences on productive-failure approach in Mamthematics

open access: yesDiversitas Journal
A learning failure is not always a denial of knowledge but an opportunity to be productive in the academic pursuit in the field of mathematics. This qualitative case study explored the students’ experiences with the utilization of the Productive-Failure
Jay Fie Luzano
doaj   +1 more source

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