Results 141 to 150 of about 2,952,128 (360)
Relative Productivity of Perforated Casing - II [PDF]
Robert A. Howard, Marsh S. Watson
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This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah+9 more
wiley +1 more source
Fading Productivity - Making Sense of Canada's Productivity Challenge [PDF]
The Global Competitiveness Report of the World Economic Forum demonstrates that Canada’s competitiveness is at its lowest in the last five years. This paper seeks to understand the major causes of the decreasing competitiveness and how these factors have
Katherine Mayman, Rock Lefebvre
core
Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li+8 more
wiley +1 more source
Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli+2 more
wiley +1 more source
The relation of tree type to productivity in the apple
Karl Sax, John W. Gowen
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A “ship‐in‐a‐bottle” strategy is used to grow oligomers inside of a MOF by crosslinking alkylamines with epoxides within the pores of Cr‐BDC. When tested in postcombustion carbon capture applications, the composites show excellent performance with high CO2 adsorption capacity, exceptional CO2/N2 selectivity, and enhanced stability over 100 adsorption ...
Jordi Espín+7 more
wiley +1 more source
Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach+4 more
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Hierarchically MOF‐Based Porous Monolith Composites for Atmospheric Water Harvesting
This review explores the design of hierarchical porous materials for atmospheric water harvesting, focusing on metal‐organic frameworks (MOFs) and porous monoliths. Emphasis is placed on integrating MOF nanoscale porosity with the microscale channels of monolithic scaffolds to enhance sorption‐desorption performance.
Mahyar Panahi‐Sarmad+7 more
wiley +1 more source