Results 141 to 150 of about 1,136,694 (293)

Regulator engagement with small business [PDF]

open access: yes, 2013
This draft report was released to assist participants in preparing a submission to the commissioned study into Regulator Engagement with Small Business. Members of the public are invited to examine this draft and provide written comment.
Productivity Commission
core  

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Increasing Australia's future prosperity - discussion paper

open access: yes, 2016
This paper was released on 7 November 2016 to assist participants in preparing a submission to the inquiry into Australia’s productivity performance. It outlines a range of issues about which the Commission is seeking information. This paper outlines:
Productivity Commission
core  

Superannuation: alternative default models [PDF]

open access: yes, 2016
This paper was released on 20 September 2016 to assist participants in preparing a submission to the public inquiry into Superannuation Alternative Default Models. It outlines a range of issues about which the Commission is seeking information.
Productivity Commission
core  

Productivity and resource allocation – Weak level and growth of productivity in Finland's digital services

open access: yes, 2021
The labour productivity gap between Finland and the world's leading countries narrowed consistently until 2008, when the trend took a downward turn. Since then the productivity gap has been widening.
Elmgren, Peter   +4 more
core  

Climate Change Threatens Micronutrient Density of European Winter Wheat

open access: yesAdvanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao   +17 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

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