Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen +6 more
wiley +1 more source
Past Performance as a Predictor of Future Success: Deciphering the Research "Arms Race" in Plastic Surgery Applicants. [PDF]
Gupta S.
europepmc +1 more source
Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos +6 more
wiley +1 more source
Prevalence and Multivariate Impact of Musculoskeletal Disorders on General Health, Occupational Fatigue, and Productivity in an Industrial Workforce. [PDF]
Choobineh A +9 more
europepmc +1 more source
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang +13 more
wiley +1 more source
A Transient Two-Phase Productivity Forecasting Method in Fractured Nanoporous Shale Gas Reservoirs. [PDF]
Zhang R, He S, Zhang Q, Xiao H, Zhang L.
europepmc +1 more source
Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng +6 more
wiley +1 more source
Individual and institutional factors linked to high research productivity among physicians in the Arab Gulf region: implications for healthcare policy. [PDF]
Al-Roomi K +8 more
europepmc +1 more source
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas +6 more
wiley +1 more source
The Multidimensional Burden of COPD in China: A Propensity Score-Matched Comparison with Other Prevalent Non-Communicable Diseases. [PDF]
Sun Q, Lu B, Chen Q, Zheng Z.
europepmc +1 more source

