Results 231 to 240 of about 1,513,546 (294)

Evaluating the Fiscal Burden of Essential Thrombocythemia in Sweden Through Application of a Government Perspective. [PDF]

Clinicoecon Outcomes Res
Copeland C, Connolly MP, Khurana V, Ottosson S, Kim I, Salomonsson S.   +5 more
europepmc   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

Does Research Predict Career Trajectory? A Nationwide Analysis of Plastic Surgery Residents From 2020 to 2024. [PDF]

Plast Reconstr Surg Glob Open
Sinha MD, York W, Agarwal P, Su S, Nores GG, Ghareeb PA.   +5 more
europepmc   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

Impact of constipation on patients with schizophrenia and depression: an internet-based survey (CONSIDER survey). [PDF]

Front Psychiatry
Hori H, Takeuchi H, Yoneda S, Shin T, Shimada Y, Umeyama M, Ueno M, Takekita Y.   +7 more
europepmc   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

Evaluating Hospital Efficiency and Productivity: A Bootstrap-Corrected DEA and Malmquist Analysis. [PDF]

Healthcare (Basel)
Poriazis C, Katharaki M, Giannakis N, Boufounou P, Tsakas M.   +4 more
europepmc   +1 more source

Factors Associated With Research Productivity Among Canadian Plastic Surgery Residents. [PDF]

Plast Surg (Oakv)
Guyn C, Lee J, Budden C.
europepmc   +1 more source

The economic imperative for an AI Productivity Index in healthcare: Beyond clinical promise to fiscal accountability. [PDF]

Clin Med (Lond)
Al-Ajlouni YA, Njei B.
europepmc   +1 more source