RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Assessment of biomass of forest species using satellite images of high spatial resolution (on the example of the forest of Khanty-Mansi autonomous okrug) [PDF]
The paper describes assessment of spatial biomass of top wood layer based on combination of high-resolution Landsat-8 satellite images and selected ground forest inventory data measurements.
E.N. Sochilova +3 more
doaj +1 more source
Assessment of direct pyrogenic carbon emissions in forests of Russia for 2020 according to remote monitoring data [PDF]
The article presents the results of an assessment of pyrogenic Carbon emissions in the forests of Russia for 2020, carried out using remote monitoring methods.
D.V. Ershov, E.N. Sochilova
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Background Being the product of the same environment, soil and vegetation are mutually associated with each other, but the relationships between edaphic properties and vegetation characteristics are still far from clear.
Natalia V. Lukina +14 more
doaj +1 more source
Assessment of biomass of forest species using satellite images of high spatial resolution (on the example of the forest of Khanty-Mansi Autonomous Okrug) [PDF]
The paper describes assessment of spatial biomass of top wood layer based on combination of high-resolution Landsat-8 satellite images and selected ground forest inventory data measurements.
E.N. Sochilova +3 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Dynamic pattern of carbon balance in the forests of federal districts of the Russian Federation [PDF]
According to the data of the State Forest Registry and the archive materials of the State Forest Fund Account carbon budget of the forests of federal districts (FDs) of Russia was calculated for the years 1988–2015.
D.G. Zamolodchikov +2 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source

