Results 131 to 140 of about 48,956 (252)

Diseño, sistema productor de sentido

open access: yesKepes, 2005
El diseño, pieza fundamental en los sistemas de producción, ha variado el rumbo hacia una nueva designación de sus productos, superando la proyectación objetual, introduciendo estrategias que impacten positivamente los sustratos culturales, reconociendo
Gustavo Villa Carmona
doaj  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Incidencia del iva en los índices de precios al consumidor y al productor

open access: yes, 2003
La presente investigación, tiene por objetivo analizar mediate herramientas estadísticas y econométricas la incidencia que tiene el I.V.A. como impuesto sobre los índices de Precios al Consumidor y al Productor., y determinar la flexibilidad que tienen ...
Moreta Zambrano, Jandry   +1 more
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

El Productor, Iquique

open access: yes, 2017
El Productor, Iquique 12/09/1921 POLITICOS NUEVOS Y NUEVAS DECLARACIONES Tiempo hacía que los políticos no nos daban alguna sorpresa que no fueran sus acostumbradas monsergas que, período tras período ritualmente declaman en son de letanías.
Cruzat Amunátegui, Ximena   +1 more
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

El pequeño productor rural y como apoyarlo

open access: yes, 1989
36 P.Las páginas que siguen se presentan para abrir una discusión sobre los pequeños productores rurales y como actuar con ellos en pro de su desarrollo.
Puerta, Ricardo
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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